STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
MJ_0736Alkyl hydroperoxide reductase; Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides. (222 aa)    
Predicted Functional Partners:
trx
Thioredoxin (trx); Acts to maintain redox homeostasis; functions as a protein disulfide reductase.
  
 0.938
MJ_0581
Conserved hypothetical protein; Does not function as a glutathione-disulfide oxidoreductase in the presence of glutathione and glutathione reductase (By similarity). Has low thioredoxin activity in vitro (By similarity).
  
 0.938
MJ_1536
Thioredoxin reductase (trxB); Similar to GB:U02197 GB:L43967 SP:P47348 PID:1045780 percent identity: 38.93; identified by sequence similarity; putative.
  
 
 0.934
MJ_0737
Rubredoxin-like non-heme iron protein; Similar to SP:P19500 percent identity: 32.56; identified by sequence similarity; putative.
  
  
 0.932
MJ_0738
Conserved hypothetical protein; Similar to GB:X69112 PID:44585 GB:AE000666 percent identity: 41.82; identified by sequence similarity; putative.
  
    0.902
MJ_0733
Hypothetical protein; Identified by GeneMark; putative; M. jannaschii predicted coding region MJ0733.
  
    0.872
MJ_0740
Rubredoxin 2 (rd2); Rubredoxin is a small nonheme, iron protein lacking acid- labile sulfide. Its single Fe, chelated to 4 Cys, functions as an electron acceptor and may also stabilize the conformation of the molecule (By similarity).
  
  
 0.872
MJ_0734
Rubrerythrin (rr); May provide oxidative stress protection via catalytic reduction of intracellular hydrogen peroxide.
  
  
 0.869
MJ_0741
Desulfoferrodoxin, putative (rbo); Uses electrons from reduced NADP, by way of rubredoxin and an oxidoreductase, to catalyze the reduction of superoxide to hydrogen peroxide.
  
  
 0.820
MJ_0967
Intracellular protease (pfpI); Similar to PID:1373331 percent identity: 33.77; identified by sequence similarity; putative; Belongs to the peptidase C56 family.
  
 
 0.794
Your Current Organism:
Methanocaldococcus jannaschii
NCBI taxonomy Id: 243232
Other names: M. jannaschii DSM 2661, Methanocaldococcus jannaschii DSM 2661, Methanocaldococcus jannaschii str. DSM 2661, Methanococcus jannaschii DSM 2661
Server load: low (24%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.