STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
fprAFlavoprotein (fpaA); Probably functions as an electron acceptor for a hydrogenase; however there is an uncharacterized intermediate between the hydrogenase and flavoprotein A; In the N-terminal section; belongs to the zinc metallo- hydrolase group 3 family. (416 aa)    
Predicted Functional Partners:
MJ_0649
NADH oxidase (nox); Catalyzes the four-electron reduction of molecular oxygen to water.
    
 0.914
MJ_0747
Hemerythrin sipunculid; Oxygen-binding protein. May be involved in a storage mechanism or for delivery to oxygen-requiring enzymes. The oxygen- binding site contains two iron atoms; Belongs to the hemerythrin family.
  
  
 0.734
MJ_0741
Desulfoferrodoxin, putative (rbo); Uses electrons from reduced NADP, by way of rubredoxin and an oxidoreductase, to catalyze the reduction of superoxide to hydrogen peroxide.
  
  
 0.596
MJ_0746
Conserved hypothetical protein; Similar to PID:710357 GB:AE000666 percent identity: 70.59; identified by sequence similarity; putative.
  
  
 0.534
MJ_0749
Conserved hypothetical protein; Similar to GP:1787226 percent identity: 31.17; identified by sequence similarity; putative.
  
  
 0.499
MJ_0735
Rubredoxin 1 (rd1); Rubredoxin is a small nonheme, iron protein lacking acid- labile sulfide. Its single Fe, chelated to 4 Cys, functions as an electron acceptor and may also stabilize the conformation of the molecule (By similarity).
 
  
 0.419
MJ_0745
Hypothetical protein; Identified by GeneMark; putative; M. jannaschii predicted coding region MJ0745; Belongs to the M.jannaschii MJ0150/MJ0739/MJ0745/MJ1460/MJ1642 family.
     
 0.405
Your Current Organism:
Methanocaldococcus jannaschii
NCBI taxonomy Id: 243232
Other names: M. jannaschii DSM 2661, Methanocaldococcus jannaschii DSM 2661, Methanocaldococcus jannaschii str. DSM 2661, Methanococcus jannaschii DSM 2661
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