STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
MJ_0760Conserved hypothetical protein; Similar to SP:P54436 PID:1303708 GB:AL009126 percent identity: 30.26; identified by sequence similarity; putative. (275 aa)    
Predicted Functional Partners:
MJ_0759
Conserved hypothetical protein; Similar to GB:AE000666 percent identity: 33.02; identified by sequence similarity; putative.
  
  
 0.994
MJ_0757
Conserved hypothetical protein; Is able to catalyze the biosynthesis of dTMP using dUMP, tetrahydrofolate and formaldehyde in vitro, i.e. a reaction equivalent to that catalyzed by bacterial thymidylate synthases (EC 2.1.1.45). However, M.jannaschii like most methanogenic Archaea lacks folates, thus the physiological cosubstrate is unknown but is likely one of the non-methylated methanopterin biosynthetic intermediates.
       0.773
MJ_0758
Hypothetical protein; Identified by GeneMark; putative; M. jannaschii predicted coding region MJ0758.
       0.773
MJ_0278
Peptidyl-prolyl cis-trans isomerase, FKBP-type rotamase (slyD); Catalyzes the cis-trans isomerization of peptidyl prolyl bonds and accelerates protein folding. Also exhibits chaperone-like activity; Belongs to the FKBP-type PPIase family.
      
 0.634
MJ_0764
Hypothetical protein; Identified by GeneMark; putative; M. jannaschii predicted coding region MJ0764.
 
    0.580
MJ_0649
NADH oxidase (nox); Catalyzes the four-electron reduction of molecular oxygen to water.
 
   
 0.544
MJ_0989
Conserved hypothetical protein; Similar to SP:P39164 GB:U00096 PID:1787471 percent identity: 28.95; identified by sequence similarity; putative; To M.kandleri MK0008.
 
     0.533
MJ_0990
Conserved hypothetical protein; Similar to GB:L13279 SP:P31065 PID:290415 GB:U00096 PID:1788239 percent identity: 39.13; identified by sequence similarity; putative; Belongs to the sulfur carrier protein TusA family.
     
 0.513
MJ_0756
Hypothetical protein; Identified by GeneMark; putative; M. jannaschii predicted coding region MJ0756.
       0.499
MJ_0762
C4-dicarboxylate transporter (mae1); Similar to SP:P50537 percent identity: 24.34; identified by sequence similarity; putative.
       0.489
Your Current Organism:
Methanocaldococcus jannaschii
NCBI taxonomy Id: 243232
Other names: M. jannaschii DSM 2661, Methanocaldococcus jannaschii DSM 2661, Methanocaldococcus jannaschii str. DSM 2661, Methanococcus jannaschii DSM 2661
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