STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
MJ_0761Conserved hypothetical protein; Similar to GB:D26185 SP:P37545 PID:467428 GB:AL009126 percent identity: 31.62; identified by sequence similarity; putative. (251 aa)    
Predicted Functional Partners:
MJ_0762
C4-dicarboxylate transporter (mae1); Similar to SP:P50537 percent identity: 24.34; identified by sequence similarity; putative.
       0.778
MJ_0763
Hypothetical protein; Identified by GeneMark; putative; M. jannaschii predicted coding region MJ0763.
       0.715
MJ_0764
Hypothetical protein; Identified by GeneMark; putative; M. jannaschii predicted coding region MJ0764.
       0.714
MJ_0757
Conserved hypothetical protein; Is able to catalyze the biosynthesis of dTMP using dUMP, tetrahydrofolate and formaldehyde in vitro, i.e. a reaction equivalent to that catalyzed by bacterial thymidylate synthases (EC 2.1.1.45). However, M.jannaschii like most methanogenic Archaea lacks folates, thus the physiological cosubstrate is unknown but is likely one of the non-methylated methanopterin biosynthetic intermediates.
       0.464
MJ_0760
Conserved hypothetical protein; Similar to SP:P54436 PID:1303708 GB:AL009126 percent identity: 30.26; identified by sequence similarity; putative.
       0.459
MJ_0759
Conserved hypothetical protein; Similar to GB:AE000666 percent identity: 33.02; identified by sequence similarity; putative.
       0.458
MJ_0758
Hypothetical protein; Identified by GeneMark; putative; M. jannaschii predicted coding region MJ0758.
       0.455
hcp
[6Fe-6S] prismane-containing protein; Catalyzes the reduction of hydroxylamine to form NH(3) and H(2)O.
       0.430
MJ_0279
4-hydroxybenzoate octaprenyltransferase (ubiA); Prenyltransferase that catalyzes the transfer of the geranylgeranyl moiety of geranylgeranyl diphosphate (GGPP) to the C2 hydroxyl of (S)-3-O-geranylgeranylglyceryl phosphate (GGGP). This reaction is the second ether-bond-formation step in the biosynthesis of archaeal membrane lipids.
 
   
 0.415
Your Current Organism:
Methanocaldococcus jannaschii
NCBI taxonomy Id: 243232
Other names: M. jannaschii DSM 2661, Methanocaldococcus jannaschii DSM 2661, Methanocaldococcus jannaschii str. DSM 2661, Methanococcus jannaschii DSM 2661
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