Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
MJ_0783Conserved hypothetical protein; Similar to GB:X73148 PID:407884 percent identity: 30.97; identified by sequence similarity; putative. (186 aa)    
Predicted Functional Partners:
MJ_1295
Conserved hypothetical protein; Similar to GP:1787520 percent identity: 31.95; identified by sequence similarity; putative.
       0.685
MJ_1388
Adenosylhomocysteinase (ahcY); Catalyzes the hydrolysis of S-inosyl-L-homocysteine (SIH) to L-homocysteine (Hcy) and inosine. Likely functions in a S-adenosyl-L- methionine (SAM) recycling pathway from S-adenosyl-L-homocysteine (SAH) produced from SAM-dependent methylation reactions. Can also catalyze the reverse reaction in vitro, i.e. the synthesis of SIH from Hcy and inosine. Is specific for SIH and inosine as it is unable to either hydrolyze SAH or synthesize SAH from adenosine and Hcy. Belongs to the adenosylhomocysteinase family.
       0.685
gltX
glutamyl-tRNA synthetase (gltX); Catalyzes the attachment of glutamate to tRNA(Glu) in a two- step reaction: glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu).
     
 0.671
MJ_0782.1
Conserved hypothetical protein; Similar to GB:AE000666 percent identity: 48.08; identified by sequence similarity; putative; To M.thermoautotrophicum MTH886.
       0.532
tfb
Transcription initiation factor IIB (TFIIB); Stabilizes TBP binding to an archaeal box-A promoter. Also responsible for recruiting RNA polymerase II to the pre-initiation complex (DNA-TBP-TFIIB).
       0.528
MJ_0215
Hypothetical protein; Identified by GeneMark; putative; M. jannaschii predicted coding region MJ0215; To M.jannaschii MJECL20.
 
     0.500
MJ_0781
Type II secretion system protein; Similar to GP:1707774 percent identity: 37.14; identified by sequence similarity; putative; Belongs to the GSP E family.
       0.449
hmd
H2-forming N5,N10-methylene-tetrahydromethanopterin dehydrogenease (hmd); Catalyzes the reversible reduction of methenyl-H(4)MPT(+) to methylene-H(4)MPT.
       0.430
MJ_0780
Hypothetical protein; Identified by GeneMark; putative; M. jannaschii predicted coding region MJ0780.
       0.418
Your Current Organism:
Methanocaldococcus jannaschii
NCBI taxonomy Id: 243232
Other names: M. jannaschii DSM 2661, Methanocaldococcus jannaschii DSM 2661, Methanocaldococcus jannaschii str. DSM 2661, Methanococcus jannaschii DSM 2661
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