STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
MJ_0783Conserved hypothetical protein; Similar to GB:X73148 PID:407884 percent identity: 30.97; identified by sequence similarity; putative. (186 aa)    
Predicted Functional Partners:
MJ_0782.1
Conserved hypothetical protein; Similar to GB:AE000666 percent identity: 48.08; identified by sequence similarity; putative; To M.thermoautotrophicum MTH886.
       0.537
tfb
Transcription initiation factor IIB (TFIIB); Stabilizes TBP binding to an archaeal box-A promoter. Also responsible for recruiting RNA polymerase II to the pre-initiation complex (DNA-TBP-TFIIB).
       0.528
metE
5-methyltetrahydropteroyltriglutamate- homocysteine methyltransferase (metE); Catalyzes the transfer of a methyl group to L-homocysteine resulting in methionine formation. Can use methylcobalamin and methylcobinamide as methyl donors, but methylcobalamin is not considered to be the physiological substrate (By similarity).
 
     0.498
MJ_1582
Conserved hypothetical protein; Similar to GB:D26185 SP:P37545 PID:467428 GB:AL009126 percent identity: 35.37; identified by sequence similarity; putative.
  
    0.461
MJ_0781
Type II secretion system protein; Similar to GP:1707774 percent identity: 37.14; identified by sequence similarity; putative; Belongs to the GSP E family.
       0.449
hmd
H2-forming N5,N10-methylene-tetrahydromethanopterin dehydrogenease (hmd); Catalyzes the reversible reduction of methenyl-H(4)MPT(+) to methylene-H(4)MPT.
       0.433
MJ_1295
Conserved hypothetical protein; Similar to GP:1787520 percent identity: 31.95; identified by sequence similarity; putative.
       0.431
MJ_1388
Adenosylhomocysteinase (ahcY); Catalyzes the hydrolysis of S-inosyl-L-homocysteine (SIH) to L-homocysteine (Hcy) and inosine. Likely functions in a S-adenosyl-L- methionine (SAM) recycling pathway from S-adenosyl-L-homocysteine (SAH) produced from SAM-dependent methylation reactions. Can also catalyze the reverse reaction in vitro, i.e. the synthesis of SIH from Hcy and inosine. Is specific for SIH and inosine as it is unable to either hydrolyze SAH or synthesize SAH from adenosine and Hcy. Belongs to the adenosylhomocysteinase family.
       0.431
MJ_1552
Conserved hypothetical protein; Similar to PID:1197355 percent identity: 48.44; identified by sequence similarity; putative.
       0.431
MJ_1656
2-hydroxyhepta-2,4-diene-1,7-dioate isomerase (hpcE); Similar to SP:P37352 GB:X75028 GB:Z37980 PID:402576 PID:757826 percent identity: 40.11; identified by sequence similarity; putative; Belongs to the FAH family.
       0.431
Your Current Organism:
Methanocaldococcus jannaschii
NCBI taxonomy Id: 243232
Other names: M. jannaschii DSM 2661, Methanocaldococcus jannaschii DSM 2661, Methanocaldococcus jannaschii str. DSM 2661, Methanococcus jannaschii DSM 2661
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