STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
MJ_0800(R)-2-hydroxyglutaryl-CoA dehydratase activator; Similar to SP:P11568 GB:X59645 PID:433932 percent identity: 31.78; identified by sequence similarity; putative. (415 aa)    
Predicted Functional Partners:
MJ_0007
2-hydroxyglutaryl-CoA dehydratase, subunit beta (hgdB); Similar to GB:X14252 SP:P11570 PID:38802 percent identity: 22.79; identified by sequence similarity; putative.
 
 0.935
MJ_1242
Methyl coenzyme M reductase system, component A2 (atwA); Similar to GB:L11748 PID:293151 PID:385924 GB:AE000666 percent identity: 60.26; identified by sequence similarity; putative; Belongs to the ABC transporter superfamily.
 
     0.778
MJ_0801
Hypothetical protein; Identified by GeneMark; putative; M. jannaschii predicted coding region MJ0801; Belongs to the archaeal ATPase family.
       0.699
MJ_0802
Conserved hypothetical protein; Similar to GB:AE000666 percent identity: 32.96; identified by sequence similarity; putative.
       0.664
cfbD
Vanadium nitrogenase-associated protein N; Involved in the biosynthesis of the unique nickel-containing tetrapyrrole coenzyme F430, the prosthetic group of methyl-coenzyme M reductase (MCR), which plays a key role in methanogenesis and anaerobic methane oxidation. Catalyzes both the six-electron reduction of the tetrahydroporphyrin ring system and the gamma-lactamization of the c- acetamide side chain of Ni-sirohydrochlorin a,c-diamide to yield 15,17(3)-seco-F430-17(3)-acid (seco-F430), the last intermediate in the biosynthesis of the coenzyme F430; Belongs to the NifD/NifK/NifE/NifN family.
  
     0.637
MJ_0799
Phosphoribosylformylglycinamidine cyclo-ligase isolog (purM); Similar to GB:J02732 SP:P12043 PID:143371 GB:AL009126 percent identity: 27.41; identified by sequence similarity; putative; To Synechocystis PCC 6803 sll0787 and M.jannaschii MJ0640.
       0.564
MJ_0798
Conserved hypothetical protein; Similar to GB:AE000666 percent identity: 30.77; identified by sequence similarity; putative.
       0.545
MJ_0797
Hypothetical protein; Similar to PID:1653948 percent identity: 28.10; identified by sequence similarity; putative.
       0.513
MJ_0796
ABC transporter, ATP-binding protein; Similar to SP:P10346 PID:581098 GB:U00096 PID:1651363 PID:1651364 percent identity: 47.83; identified by sequence similarity; putative; Belongs to the ABC transporter superfamily.
       0.497
MJ_0796.1
Hypothetical protein; Brute Force ORF; identified by GeneMark; putative; M. jannaschii predicted coding region MJ0796.1.
       0.497
Your Current Organism:
Methanocaldococcus jannaschii
NCBI taxonomy Id: 243232
Other names: M. jannaschii DSM 2661, Methanocaldococcus jannaschii DSM 2661, Methanocaldococcus jannaschii str. DSM 2661, Methanococcus jannaschii DSM 2661
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