Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
MJ_0808Pyruvate-formate-lyase-activating enzyme (act); Similar to PID:1072362 SP:Q46267 percent identity: 30.41; identified by sequence similarity; putative. (333 aa)    
Predicted Functional Partners:
MJ_0810
Conserved hypothetical protein; Similar to GP:949850 percent identity: 33.11; identified by sequence similarity; putative.
     0.986
MJ_0403
Conserved hypothetical protein; Similar to GP:1707828 percent identity: 48.03; identified by sequence similarity; putative; Belongs to the MEMO1 family.
     0.955
MJ_0807
Conserved hypothetical protein; Similar to GB:AE000782 percent identity: 44.68; identified by sequence similarity; putative; Belongs to the chorismate pyruvate-lyase type 2 family.
  
    0.936
MJ_0832
Anaerobic ribonucleoside-triphosphate reductase (nrdD); Similar to SP:P28903 GB:L06097 GB:U06195 GB:Z46865 PID:146970 percent identity: 28.17; identified by sequence similarity; putative.
  
  
 0.747
thiL
Thiamine monphosphate kinase (thiL); Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1; Belongs to the thiamine-monophosphate kinase family.
       0.685
MJ_0538
Hypothetical protein; Identified by GeneMark; putative; M. jannaschii predicted coding region MJ0538.
       0.685
sla
S-layer structural protein; S-layer protein. The S-layer is a paracrystalline mono- layered assembly of proteins which coat the surface of the cell. Belongs to the Mj S-layer protein family.
       0.685
MJ_0043
Intein containing hypothetical protein; Similar to GP:1303985 percent identity: 41.38; identified by sequence similarity; putative.
       0.649
MJ_1595
Conserved hypothetical protein; Similar to GB:AE000666 percent identity: 27.66; identified by sequence similarity; putative.
       0.640
moaA
Molybdenum cofactor biosynthesis protein (moaA); Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate; Belongs to the radical SAM superfamily. MoaA family.
  
  
 0.505
Your Current Organism:
Methanocaldococcus jannaschii
NCBI taxonomy Id: 243232
Other names: M. jannaschii DSM 2661, Methanocaldococcus jannaschii DSM 2661, Methanocaldococcus jannaschii str. DSM 2661, Methanococcus jannaschii DSM 2661
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