Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
slaS-layer structural protein; S-layer protein. The S-layer is a paracrystalline mono- layered assembly of proteins which coat the surface of the cell. Belongs to the Mj S-layer protein family. (558 aa)    
Predicted Functional Partners:
MJ_0818
Hypothetical protein; Identified by GeneMark; putative; M. jannaschii predicted coding region MJ0818.
       0.769
MJ_0538
Hypothetical protein; Identified by GeneMark; putative; M. jannaschii predicted coding region MJ0538.
       0.685
MJ_0808
Pyruvate-formate-lyase-activating enzyme (act); Similar to PID:1072362 SP:Q46267 percent identity: 30.41; identified by sequence similarity; putative.
       0.685
thiL
Thiamine monphosphate kinase (thiL); Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1; Belongs to the thiamine-monophosphate kinase family.
       0.653
MJ_0821
Hypothetical protein; Identified by GeneMark; putative; M. jannaschii predicted coding region MJ0821; Belongs to the archaeal ATPase family.
       0.574
tfb
Transcription initiation factor IIB (TFIIB); Stabilizes TBP binding to an archaeal box-A promoter. Also responsible for recruiting RNA polymerase II to the pre-initiation complex (DNA-TBP-TFIIB).
      
 0.476
MJ_0449
Hypothetical transmembrane protein yeaB; Similar to GP:1708640 percent identity: 31.05; identified by sequence similarity; putative.
   
    0.433
pyrE
Orotate phosphoribosyl transferase (pyrE); Catalyzes the transfer of a ribosyl phosphate group from 5- phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP).
      
 0.429
Your Current Organism:
Methanocaldococcus jannaschii
NCBI taxonomy Id: 243232
Other names: M. jannaschii DSM 2661, Methanocaldococcus jannaschii DSM 2661, Methanocaldococcus jannaschii str. DSM 2661, Methanococcus jannaschii DSM 2661
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