Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
MJ_0826Conserved hypothetical protein; Similar to GP:1786696 percent identity: 24.82; identified by sequence similarity; putative. (138 aa)    
Predicted Functional Partners:
MJ_0827
Membrane protein, putative regulator of cation conductance; Similar to GB:M81635 GB:X60067 SP:P27105 PID:1161562 PID:181184 percent identity: 42.63; identified by sequence similarity; putative.
 
 
 0.969
MJ_0828
Conserved hypothetical protein; Similar to GB:M35130 PID:150075 percent identity: 66.15; identified by sequence similarity; putative.
  
 
 0.948
cobS
Cobalamin (5'-phosphate) synthase (cobS); Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'- phosphate; Belongs to the CobS family.
 
    0.849
MJ_0825
Peptidyl-prolyl cis-trans isomerase, FKBP-type rotamase (slyD); Catalyzes the cis-trans isomerization of peptidyl prolyl bonds and accelerates protein folding (By similarity). Also exhibits chaperone-like activity. Belongs to the FKBP-type PPIase family.
       0.525
prf1
Peptide chain release factor aRF, subunit 1; Directs the termination of nascent peptide synthesis (translation) in response to the termination codons UAA, UAG and UGA.
       0.518
MJ_0066
Sulfate adenylate transferase, subunit 2 (cysD); Similar to SP:Q10599 PID:1322409 percent identity: 28.80; identified by sequence similarity; putative; In the C-terminal section; belongs to the PAPS reductase family.
 
     0.507
flaH
Flagella-related protein H, putative; Similar to GP:2104780 percent identity: 67.39; identified by sequence similarity; putative.
  
     0.492
flaJ
Conserved hypothetical protein; Similar to GB:AE000782 percent identity: 28.40; identified by sequence similarity; putative; To M.jannaschii MJ1286.
  
     0.485
cbiH
Cobalamin biosynthesis precorrin-3 methylase (cbiH); Methyltransferase that likely catalyzes the ring contraction and methylation of C-17 in cobalt-factor III to form cobalt-factor IV. May also convert cobalt-precorrin-3 to cobalt-precorrin-4 (By similarity).
  
    0.484
MJ_0108
Pyruvate kinase; Similar to GB:D13095 SP:Q02499 GB:X57859 PID:285623 percent identity: 38.82; identified by sequence similarity; putative.
     
 0.463
Your Current Organism:
Methanocaldococcus jannaschii
NCBI taxonomy Id: 243232
Other names: M. jannaschii DSM 2661, Methanocaldococcus jannaschii DSM 2661, Methanocaldococcus jannaschii str. DSM 2661, Methanococcus jannaschii DSM 2661
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