STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
MJ_0828Conserved hypothetical protein; Similar to GB:M35130 PID:150075 percent identity: 66.15; identified by sequence similarity; putative. (66 aa)    
Predicted Functional Partners:
MJ_0827
Membrane protein, putative regulator of cation conductance; Similar to GB:M81635 GB:X60067 SP:P27105 PID:1161562 PID:181184 percent identity: 42.63; identified by sequence similarity; putative.
      0.965
MJ_0826
Conserved hypothetical protein; Similar to GP:1786696 percent identity: 24.82; identified by sequence similarity; putative.
  
  
 0.899
MJ_0920
GTP-binding protein homologue (yphC); Similar to PID:1146219 SP:P50743 GB:AL009126 percent identity: 26.99; identified by sequence similarity; putative.
  
 0.653
asd-2
Phosphatidylserine decarboxylase proenzyme 2 precursor (psd2); Catalyzes the formation of archaetidylethanolamine (PtdEtn) from archaetidylserine (PtdSer); Belongs to the phosphatidylserine decarboxylase family. PSD-A subfamily.
   
 
 0.652
pan
Proteasome regulatory AAA-ATPase; ATPase which is responsible for recognizing, binding, unfolding and translocation of substrate proteins into the archaeal 20S proteasome core particle. Is essential for opening the gate of the 20S proteasome via an interaction with its C-terminus, thereby allowing substrate entry and access to the site of proteolysis. Thus, the C- termini of the proteasomal ATPase function like a 'key in a lock' to induce gate opening and therefore regulate proteolysis. Unfolding activity requires energy from ATP hydrolysis, whereas ATP binding alone promotes ATPase-20 [...]
  
 
 0.620
MJ_1226
Plasma membrane ATPase 1 (aha1); Similar to SP:P20649 percent identity: 44.42; identified by sequence similarity; putative; Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IIIA subfamily.
   
 0.576
MJ_0825
Peptidyl-prolyl cis-trans isomerase, FKBP-type rotamase (slyD); Catalyzes the cis-trans isomerization of peptidyl prolyl bonds and accelerates protein folding (By similarity). Also exhibits chaperone-like activity. Belongs to the FKBP-type PPIase family.
  
  
 0.537
prf1
Peptide chain release factor aRF, subunit 1; Directs the termination of nascent peptide synthesis (translation) in response to the termination codons UAA, UAG and UGA.
     
 0.536
hflX
GTP-binding protein, member of GTP1/OBG-family; GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis. Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. HflX GTPase family.
  
  
 0.508
MJ_1417
ATP-dependent protease LA, putative (lon); ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short- lived regulatory proteins. Degrades polypeptides processively (By similarity).
  
 
 0.447
Your Current Organism:
Methanocaldococcus jannaschii
NCBI taxonomy Id: 243232
Other names: M. jannaschii DSM 2661, Methanocaldococcus jannaschii DSM 2661, Methanocaldococcus jannaschii str. DSM 2661, Methanococcus jannaschii DSM 2661
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