STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
rnjConserved hypothetical protein; An RNase that has 5'-3' exonuclease activity. May be involved in RNA degradation; Belongs to the metallo-beta-lactamase superfamily. RNA- metabolizing metallo-beta-lactamase-like family. Archaeal RNase J subfamily. (448 aa)    
Predicted Functional Partners:
idsA
Bifunctional short chain isoprenyl diphosphate synthase (idsA); Similar to PID:913252 SP:Q53479 percent identity: 48.47; identified by sequence similarity; putative.
  
    0.994
MJ_1236
Putative mRNA 3'-end processing factor 2; Similar to GP:1707412 percent identity: 32.61; identified by sequence similarity; putative.
      
 0.905
MJ_0162
Putative mRNA 3'-end processing factor 3; Similar to GP:1707412 percent identity: 35.48; identified by sequence similarity; putative; Belongs to the metallo-beta-lactamase superfamily. RNA- metabolizing metallo-beta-lactamase-like family.
      
 0.874
fni
Carotenoid biosynthetic gene ERWCRTS isolog; Involved in the biosynthesis of isoprenoids. Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its allylic isomer, dimethylallyl diphosphate (DMAPP).
  
    0.868
dapA
Dihydrodipicolinate synthase (dapA); Catalyzes the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to 4-hydroxy-tetrahydrodipicolinate (HTPA).
 
  
 0.853
rnz
Conserved hypothetical protein; Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA; Belongs to the RNase Z family.
     
 0.839
MJ_0859
Hypothetical protein; Identified by GeneMark; putative; M. jannaschii predicted coding region MJ0859.
       0.776
crcB
Conserved hypothetical protein; Important for reducing fluoride concentration in the cell, thus reducing its toxicity; Belongs to the CrcB (TC 9.B.71) family.
     
 0.754
rps15
SSU ribosomal protein S15P (rpsO); Similar to GP:297071 percent identity: 48.34; identified by sequence similarity; putative.
  
  
 0.738
rpl37ae
LSU ribosomal protein L37AE; Binds to the 23S rRNA.
   
    0.715
Your Current Organism:
Methanocaldococcus jannaschii
NCBI taxonomy Id: 243232
Other names: M. jannaschii DSM 2661, Methanocaldococcus jannaschii DSM 2661, Methanocaldococcus jannaschii str. DSM 2661, Methanococcus jannaschii DSM 2661
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