| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| MJ_0044 | MJ_1546 | MJ_0044 | MJ_1546 | Conserved hypothetical protein; Catalyzes the formation of isopentenyl diphosphate (IPP), the building block of all isoprenoids. Has no activity with farnesyl phosphate; Belongs to the isopentenyl phosphate kinase family. | Putative beta-ketoacyl acyl-carrier-protein synthase (fabH); Similar to PID:1197357 percent identity: 64.20; identified by sequence similarity; putative; Belongs to the thiolase-like superfamily. UPF0219 family. | 0.460 |
| MJ_0044 | fni | MJ_0044 | MJ_0862 | Conserved hypothetical protein; Catalyzes the formation of isopentenyl diphosphate (IPP), the building block of all isoprenoids. Has no activity with farnesyl phosphate; Belongs to the isopentenyl phosphate kinase family. | Carotenoid biosynthetic gene ERWCRTS isolog; Involved in the biosynthesis of isoprenoids. Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its allylic isomer, dimethylallyl diphosphate (DMAPP). | 0.955 |
| MJ_0044 | idsA | MJ_0044 | MJ_0860 | Conserved hypothetical protein; Catalyzes the formation of isopentenyl diphosphate (IPP), the building block of all isoprenoids. Has no activity with farnesyl phosphate; Belongs to the isopentenyl phosphate kinase family. | Bifunctional short chain isoprenyl diphosphate synthase (idsA); Similar to PID:913252 SP:Q53479 percent identity: 48.47; identified by sequence similarity; putative. | 0.953 |
| MJ_0044 | mvk | MJ_0044 | MJ_1087 | Conserved hypothetical protein; Catalyzes the formation of isopentenyl diphosphate (IPP), the building block of all isoprenoids. Has no activity with farnesyl phosphate; Belongs to the isopentenyl phosphate kinase family. | Mevalonate kinase; Catalyzes the phosphorylation of (R)-mevalonate (MVA) to (R)- mevalonate 5-phosphate (MVAP). Functions in the mevalonate (MVA) pathway leading to isopentenyl diphosphate (IPP), a key precursor for the biosynthesis of isoprenoid compounds such as archaeal membrane lipids; Belongs to the GHMP kinase family. Mevalonate kinase subfamily. | 0.645 |
| MJ_0044 | rnj | MJ_0044 | MJ_0861 | Conserved hypothetical protein; Catalyzes the formation of isopentenyl diphosphate (IPP), the building block of all isoprenoids. Has no activity with farnesyl phosphate; Belongs to the isopentenyl phosphate kinase family. | Conserved hypothetical protein; An RNase that has 5'-3' exonuclease activity. May be involved in RNA degradation; Belongs to the metallo-beta-lactamase superfamily. RNA- metabolizing metallo-beta-lactamase-like family. Archaeal RNase J subfamily. | 0.516 |
| MJ_0092 | fni | MJ_0092 | MJ_0862 | Heterodisulfide reductase, subunit D (hdrD); Similar to GP:1890198 percent identity: 31.87; identified by sequence similarity; putative; Belongs to the succinate dehydrogenase/fumarate reductase iron-sulfur protein family. | Carotenoid biosynthetic gene ERWCRTS isolog; Involved in the biosynthesis of isoprenoids. Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its allylic isomer, dimethylallyl diphosphate (DMAPP). | 0.718 |
| MJ_0092 | hypA | MJ_0092 | MJ_0214 | Heterodisulfide reductase, subunit D (hdrD); Similar to GP:1890198 percent identity: 31.87; identified by sequence similarity; putative; Belongs to the succinate dehydrogenase/fumarate reductase iron-sulfur protein family. | Hydrogenase expression/formation protein (hypA); Involved in the maturation of [NiFe] hydrogenases. Required for nickel insertion into the metal center of the hydrogenase. | 0.467 |
| MJ_1546 | MJ_0044 | MJ_1546 | MJ_0044 | Putative beta-ketoacyl acyl-carrier-protein synthase (fabH); Similar to PID:1197357 percent identity: 64.20; identified by sequence similarity; putative; Belongs to the thiolase-like superfamily. UPF0219 family. | Conserved hypothetical protein; Catalyzes the formation of isopentenyl diphosphate (IPP), the building block of all isoprenoids. Has no activity with farnesyl phosphate; Belongs to the isopentenyl phosphate kinase family. | 0.460 |
| MJ_1546 | fni | MJ_1546 | MJ_0862 | Putative beta-ketoacyl acyl-carrier-protein synthase (fabH); Similar to PID:1197357 percent identity: 64.20; identified by sequence similarity; putative; Belongs to the thiolase-like superfamily. UPF0219 family. | Carotenoid biosynthetic gene ERWCRTS isolog; Involved in the biosynthesis of isoprenoids. Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its allylic isomer, dimethylallyl diphosphate (DMAPP). | 0.687 |
| MJ_1546 | idsA | MJ_1546 | MJ_0860 | Putative beta-ketoacyl acyl-carrier-protein synthase (fabH); Similar to PID:1197357 percent identity: 64.20; identified by sequence similarity; putative; Belongs to the thiolase-like superfamily. UPF0219 family. | Bifunctional short chain isoprenyl diphosphate synthase (idsA); Similar to PID:913252 SP:Q53479 percent identity: 48.47; identified by sequence similarity; putative. | 0.731 |
| MJ_1546 | mvk | MJ_1546 | MJ_1087 | Putative beta-ketoacyl acyl-carrier-protein synthase (fabH); Similar to PID:1197357 percent identity: 64.20; identified by sequence similarity; putative; Belongs to the thiolase-like superfamily. UPF0219 family. | Mevalonate kinase; Catalyzes the phosphorylation of (R)-mevalonate (MVA) to (R)- mevalonate 5-phosphate (MVAP). Functions in the mevalonate (MVA) pathway leading to isopentenyl diphosphate (IPP), a key precursor for the biosynthesis of isoprenoid compounds such as archaeal membrane lipids; Belongs to the GHMP kinase family. Mevalonate kinase subfamily. | 0.883 |
| cooS | fni | MJ_0728 | MJ_0862 | Carbon monoxide dehydrogenase, catalytic subunit (cooS); CODH oxidizes carbon monoxide coupled, via CooF, to the reduction of a hydrogen cation by a hydrogenase (possibly CooH). | Carotenoid biosynthetic gene ERWCRTS isolog; Involved in the biosynthesis of isoprenoids. Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its allylic isomer, dimethylallyl diphosphate (DMAPP). | 0.737 |
| cooS | hypA | MJ_0728 | MJ_0214 | Carbon monoxide dehydrogenase, catalytic subunit (cooS); CODH oxidizes carbon monoxide coupled, via CooF, to the reduction of a hydrogen cation by a hydrogenase (possibly CooH). | Hydrogenase expression/formation protein (hypA); Involved in the maturation of [NiFe] hydrogenases. Required for nickel insertion into the metal center of the hydrogenase. | 0.841 |
| fni | MJ_0044 | MJ_0862 | MJ_0044 | Carotenoid biosynthetic gene ERWCRTS isolog; Involved in the biosynthesis of isoprenoids. Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its allylic isomer, dimethylallyl diphosphate (DMAPP). | Conserved hypothetical protein; Catalyzes the formation of isopentenyl diphosphate (IPP), the building block of all isoprenoids. Has no activity with farnesyl phosphate; Belongs to the isopentenyl phosphate kinase family. | 0.955 |
| fni | MJ_0092 | MJ_0862 | MJ_0092 | Carotenoid biosynthetic gene ERWCRTS isolog; Involved in the biosynthesis of isoprenoids. Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its allylic isomer, dimethylallyl diphosphate (DMAPP). | Heterodisulfide reductase, subunit D (hdrD); Similar to GP:1890198 percent identity: 31.87; identified by sequence similarity; putative; Belongs to the succinate dehydrogenase/fumarate reductase iron-sulfur protein family. | 0.718 |
| fni | MJ_1546 | MJ_0862 | MJ_1546 | Carotenoid biosynthetic gene ERWCRTS isolog; Involved in the biosynthesis of isoprenoids. Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its allylic isomer, dimethylallyl diphosphate (DMAPP). | Putative beta-ketoacyl acyl-carrier-protein synthase (fabH); Similar to PID:1197357 percent identity: 64.20; identified by sequence similarity; putative; Belongs to the thiolase-like superfamily. UPF0219 family. | 0.687 |
| fni | cooS | MJ_0862 | MJ_0728 | Carotenoid biosynthetic gene ERWCRTS isolog; Involved in the biosynthesis of isoprenoids. Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its allylic isomer, dimethylallyl diphosphate (DMAPP). | Carbon monoxide dehydrogenase, catalytic subunit (cooS); CODH oxidizes carbon monoxide coupled, via CooF, to the reduction of a hydrogen cation by a hydrogenase (possibly CooH). | 0.737 |
| fni | hypA | MJ_0862 | MJ_0214 | Carotenoid biosynthetic gene ERWCRTS isolog; Involved in the biosynthesis of isoprenoids. Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its allylic isomer, dimethylallyl diphosphate (DMAPP). | Hydrogenase expression/formation protein (hypA); Involved in the maturation of [NiFe] hydrogenases. Required for nickel insertion into the metal center of the hydrogenase. | 0.749 |
| fni | hypB | MJ_0862 | MJ_0442 | Carotenoid biosynthetic gene ERWCRTS isolog; Involved in the biosynthesis of isoprenoids. Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its allylic isomer, dimethylallyl diphosphate (DMAPP). | Hydrogenase expression/formation protein (hypB); Involved in the maturation of [NiFe] hydrogenases. Required for nickel insertion into the metal center of the hydrogenase. Exhibits a low intrinsic GTPase activity, which is essential for nickel insertion; Belongs to the SIMIBI class G3E GTPase family. HypB/HupM subfamily. | 0.713 |
| fni | idsA | MJ_0862 | MJ_0860 | Carotenoid biosynthetic gene ERWCRTS isolog; Involved in the biosynthesis of isoprenoids. Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its allylic isomer, dimethylallyl diphosphate (DMAPP). | Bifunctional short chain isoprenyl diphosphate synthase (idsA); Similar to PID:913252 SP:Q53479 percent identity: 48.47; identified by sequence similarity; putative. | 0.980 |