STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
fsrCoenzyme F420-reducing hydrogenase, beta subunit (frhB); Catalyzes the reduction of sulfite to sulfide using reduced F420 as the electron source. Involved in sulfite detoxification and assimilation. Cannot use NADH or NADPH; Belongs to the nitrite and sulfite reductase 4Fe-4S domain family. (620 aa)    
Predicted Functional Partners:
fprA
Flavoprotein (fpaA); Probably functions as an electron acceptor for a hydrogenase; however there is an uncharacterized intermediate between the hydrogenase and flavoprotein A; In the N-terminal section; belongs to the zinc metallo- hydrolase group 3 family.
     
 0.734
MJ_0973
3-phosphoadenosine 5-phosphosulfate sulfotransferase (cysH); Similar to GB:M23008 SP:P17854 GB:Y07525 PID:145682 PID:41198 percent identity: 28.57; identified by sequence similarity; putative; In the C-terminal section; belongs to the PAPS reductase family.
  
  
 0.733
frhG
Coenzyme F420-reducing hydrogenase, gamma subunit; Reduces the physiological low-potential two-electron acceptor coenzyme F420, and the artificial one-electron acceptor methylviologen.
      
 0.725
MJ_0649
NADH oxidase (nox); Catalyzes the four-electron reduction of molecular oxygen to water.
   
 0.725
MJ_0871
Conserved hypothetical protein; Similar to GB:AE000782 percent identity: 39.58; identified by sequence similarity; putative.
       0.516
fdhB
Formate dehydrogenase, beta subunit; Catalyzes the oxidation of formate; Belongs to the FrhB family.
 
   
0.471
MJ_1662
Methyl coenzyme M reductase system, component A2-like; Similar to GB:L11748 PID:293151 PID:385924 GB:AE000666 percent identity: 37.07; identified by sequence similarity; putative; Belongs to the ABC transporter superfamily.
 
     0.417
Your Current Organism:
Methanocaldococcus jannaschii
NCBI taxonomy Id: 243232
Other names: M. jannaschii DSM 2661, Methanocaldococcus jannaschii DSM 2661, Methanocaldococcus jannaschii str. DSM 2661, Methanococcus jannaschii DSM 2661
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