STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
MJ_0871Conserved hypothetical protein; Similar to GB:AE000782 percent identity: 39.58; identified by sequence similarity; putative. (317 aa)    
Predicted Functional Partners:
bioB
Biotin synthetase (bioB); Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical-based mechanism; Belongs to the radical SAM superfamily. Biotin synthase family.
   
    0.772
artE
Hypothetical protein; Transpeptidase that recognizes and modifies its substrate by proteolytic cleavage of a sorting signal. Following cleavage, a covalent intermediate is formed via a thioester bond between the archaeosortase and its substrate, which is then transferred and covalently attached to the cell membrane.
   
    0.653
MJ_0296
Hypothetical protein; Identified by GeneMark; putative; M. jannaschii predicted coding region MJ0296.
 
    0.543
fsr
Coenzyme F420-reducing hydrogenase, beta subunit (frhB); Catalyzes the reduction of sulfite to sulfide using reduced F420 as the electron source. Involved in sulfite detoxification and assimilation. Cannot use NADH or NADPH; Belongs to the nitrite and sulfite reductase 4Fe-4S domain family.
       0.516
rpoL
DNA-directed RNA polymerase, subunit L (rpoL); DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
  
     0.492
MJ_0096
Hypothetical protein; Identified by GeneMark; putative; M. jannaschii predicted coding region MJ0096.
   
    0.465
MJ_0420
O-antigen polymerase isolog; Similar to GB:M60066 SP:P26479 PID:154343 percent identity: 26.15; identified by sequence similarity; putative.
   
    0.463
MJ_0670
Conserved hypothetical protein; Similar to GB:AE000666 percent identity: 37.37; identified by sequence similarity; putative.
   
    0.463
MJ_0733
Hypothetical protein; Identified by GeneMark; putative; M. jannaschii predicted coding region MJ0733.
  
     0.423
Your Current Organism:
Methanocaldococcus jannaschii
NCBI taxonomy Id: 243232
Other names: M. jannaschii DSM 2661, Methanocaldococcus jannaschii DSM 2661, Methanocaldococcus jannaschii str. DSM 2661, Methanococcus jannaschii DSM 2661
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