STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
MJ_0886Molybdenum cofactor biosynthesis protein (moeA); Similar to GB:M21151 SP:P12281 PID:145539 GB:U00096 PID:1651376 percent identity: 34.44; identified by sequence similarity; putative. (620 aa)    
Predicted Functional Partners:
moaB
Molybdenum cofactor biosynthesis protein (moaB); Catalyzes the adenylation of molybdopterin as part of the biosynthesis of the molybdenum-cofactor.
 
 0.974
mobA
Molybdopterin-guanine dinucleotide biosynthesis protein A (mobA); Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo-MPT) cofactor (Moco or molybdenum cofactor) to form Mo-molybdopterin guanine dinucleotide (Mo-MGD) cofactor.
 
 0.965
cofC
Conserved hypothetical protein; Guanylyltransferase that catalyzes the activation of phosphoenolpyruvate (PEP) as enolpyruvoyl-2-diphospho-5'-guanosine, via the condensation of PEP with GTP. It is involved in the biosynthesis of coenzyme F420, a hydride carrier cofactor. Is able to utilize other purine nucleotides including ATP, dGTP and ITP as cosubstrates in place of GTP but with a lower activity. Does not display lactate kinase activity.
       0.952
MJ_0666
Molybdenum cofactor biosynthesis protein (moeA); Similar to GB:L42023 SP:P45210 PID:1007555 PID:1221592 PID:1205684 percent identity: 33.51; identified by sequence similarity; putative.
 
  
 
0.945
moaC
Molybdenum cofactor biosynthesis protein (moaC); Catalyzes the conversion of (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate to cyclic pyranopterin monophosphate (cPMP); Belongs to the MoaC family.
  
 0.830
moaA
Molybdenum cofactor biosynthesis protein (moaA); Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate; Belongs to the radical SAM superfamily. MoaA family.
 
 0.800
MJ_0888
Conserved hypothetical protein; Similar to SP:P54501 PID:1303871 GB:AL009126 percent identity: 28.66; identified by sequence similarity; putative.
  
  
 0.796
mobB
Molybdopterin-guanine dinucleotide biosynthesis protein B (mobB); GTP-binding protein that is not required for the biosynthesis of Mo-molybdopterin guanine dinucleotide (Mo-MGD) cofactor, and not necessary for the formation of active molybdoenzymes using this form of molybdenum cofactor. May act as an adapter protein to achieve the efficient biosynthesis and utilization of MGD. Displays a weak intrinsic GTPase activity (By similarity); Belongs to the MobB family.
 
 
 0.792
MJ_0717
Molybdopterin converting factor, subunit 2 (moaE); Similar to GB:X70420 SP:P30749 PID:42012 GB:U00096 PID:1787003 percent identity: 31.52; identified by sequence similarity; putative; To Synechocystis PCC 6803 slr0903.
  
  
 0.720
pol
DNA polymerase B1; Similar to GB:D29671 PID:473967 PID:1620911 percent identity: 46.87; identified by sequence similarity; putative; Belongs to the DNA polymerase type-B family.
       0.662
Your Current Organism:
Methanocaldococcus jannaschii
NCBI taxonomy Id: 243232
Other names: M. jannaschii DSM 2661, Methanocaldococcus jannaschii DSM 2661, Methanocaldococcus jannaschii str. DSM 2661, Methanococcus jannaschii DSM 2661
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