STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
MJ_0912Conserved hypothetical protein; Similar to GP:1788638 percent identity: 31.17; identified by sequence similarity; putative. (243 aa)    
Predicted Functional Partners:
MJ_0920
GTP-binding protein homologue (yphC); Similar to PID:1146219 SP:P50743 GB:AL009126 percent identity: 26.99; identified by sequence similarity; putative.
  
 0.852
eif2a
Translation initiation factor aIF-2, subunit alpha (aif2A); eIF-2 functions in the early steps of protein synthesis by forming a ternary complex with GTP and initiator tRNA; Belongs to the eIF-2-alpha family.
  
 
 0.814
rpl7ae
LSU ribosomal protein L7AE; Multifunctional RNA-binding protein that recognizes the K- turn motif in ribosomal RNA, the RNA component of RNase P, box H/ACA, box C/D and box C'/D' sRNAs; Belongs to the eukaryotic ribosomal protein eL8 family.
   
 0.806
rpl14e
LSU ribosomal protein L14E; Similar to SP:P36105 SP:P38754 PID:2131109 PID:485979 PID:500817 percent identity: 36.36; identified by sequence similarity; putative; Belongs to the eukaryotic ribosomal protein eL14 family.
   
 0.803
rpl3
LSU ribosomal protein L3P (rplC); One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit; Belongs to the universal ribosomal protein uL3 family.
  
 0.802
rpl10
LSU ribosomal protein L10E; Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors. Belongs to the universal ribosomal protein uL10 family.
  
 0.801
MJ_0047
Putative mRNA 3'-end processing factor 1; Similar to GP:1707412 percent identity: 30.64; identified by sequence similarity; putative; Belongs to the metallo-beta-lactamase superfamily. RNA- metabolizing metallo-beta-lactamase-like family.
  
 
 0.787
MJ_0162
Putative mRNA 3'-end processing factor 3; Similar to GP:1707412 percent identity: 35.48; identified by sequence similarity; putative; Belongs to the metallo-beta-lactamase superfamily. RNA- metabolizing metallo-beta-lactamase-like family.
  
 
 0.787
ths
Thermosome (ths); Molecular chaperone; binds unfolded polypeptides in vitro, and has a weak ATPase activity; Belongs to the TCP-1 chaperonin family.
  
 
 0.782
coaBC
Pantothenate metabolism flavoprotein (dfp); Catalyzes two sequential steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'- phosphopantothenate to form 4-phosphopantothenoylcysteine. In the second step the latter compound is decarboxylated to form 4'- phosphopantotheine; In the C-terminal section; belongs to the PPC synthetase family.
   
 
 0.772
Your Current Organism:
Methanocaldococcus jannaschii
NCBI taxonomy Id: 243232
Other names: M. jannaschii DSM 2661, Methanocaldococcus jannaschii DSM 2661, Methanocaldococcus jannaschii str. DSM 2661, Methanococcus jannaschii DSM 2661
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