STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
nadXConserved hypothetical protein; Specifically catalyzes the NAD or NADP-dependent dehydrogenation of L-aspartate to iminoaspartate. (267 aa)    
Predicted Functional Partners:
nadA
Quinolinate synthetase (nadA); Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate.
    
 0.950
MJ_0916
Conserved hypothetical protein; Similar to GB:AE000782 percent identity: 41.27; identified by sequence similarity; putative.
  
    0.816
argG
Argininosuccinate synthetase (argG); Similar to GB:M21315 SP:P13256 PID:150046 percent identity: 71.90; identified by sequence similarity; putative; Belongs to the argininosuccinate synthase family. Type 1 subfamily.
   
 
  0.811
pyrI
Aspartate carbamoyltransferase regulatory chain (pyrI); Involved in allosteric regulation of aspartate carbamoyltransferase.
    
  0.808
MJ_0001
Aspartate aminotransferase (aspB1); Similar to PID:1146246 SP:P53001 GB:AL009126 percent identity: 44.38; identified by sequence similarity; putative; Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.
    
  0.806
purA
Adenylosuccinate synthetase (purA); Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP; Belongs to the adenylosuccinate synthetase family.
     
  0.800
MJ_1056
Asparagine synthetase (asnB); Similar to GB:J05554 SP:P22106 PID:145393 GB:U00096 PID:1651277 percent identity: 32.95; identified by sequence similarity; putative; Belongs to the asparagine synthetase family.
     
  0.800
MJ_1116
Asparagine synthetase (asnB); Similar to GB:J05554 SP:P22106 PID:145393 GB:U00096 PID:1651277 percent identity: 33.78; identified by sequence similarity; putative; Belongs to the asparagine synthetase family.
     
  0.800
pyrB
Aspartate carbamoyltransferase catalytic chain (pyrB); Similar to GP:1572497 percent identity: 59.12; identified by sequence similarity; putative.
     
  0.800
coaBC
Pantothenate metabolism flavoprotein (dfp); Catalyzes two sequential steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'- phosphopantothenate to form 4-phosphopantothenoylcysteine. In the second step the latter compound is decarboxylated to form 4'- phosphopantotheine; In the C-terminal section; belongs to the PPC synthetase family.
       0.791
Your Current Organism:
Methanocaldococcus jannaschii
NCBI taxonomy Id: 243232
Other names: M. jannaschii DSM 2661, Methanocaldococcus jannaschii DSM 2661, Methanocaldococcus jannaschii str. DSM 2661, Methanococcus jannaschii DSM 2661
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