Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
MJ_0927Conserved hypothetical protein; DNA-binding protein exhibiting the ability to bind to both single-stranded and double-stranded DNA; Belongs to the GTP cyclohydrolase I type 2/NIF3 family. (249 aa)    
Predicted Functional Partners:
MJ_0928
Protoporphyrinogen oxidase (hemK); Putative protein methyltransferase using S-adenosyl-L- methionine as the methyl donor. May methylate a Gln residue in target proteins (By similarity); Belongs to the eukaryotic/archaeal PrmC-related family.
  
    0.945
MJ_0489
Conserved hypothetical protein; Similar to PID:726060 GB:AE000666 percent identity: 36.80; identified by sequence similarity; putative.
       0.647
MJ_1251
Conserved hypothetical protein; Similar to PID:726072 percent identity: 37.75; identified by sequence similarity; putative; Belongs to the UPF0254 family.
       0.629
MJ_0488
Conserved hypothetical protein; Similar to GB:AE000666 percent identity: 47.74; identified by sequence similarity; putative.
       0.600
MJ_0693
Conserved hypothetical protein; Similar to PID:726058 GB:AE000666 percent identity: 44.93; identified by sequence similarity; putative.
       0.581
MJ_1136
Conserved hypothetical protein; tRNA uridine(34) acetyltransferase, which mediates formation of carboxymethyluridine in the wobble base at position 34 in tRNAs. The proposed mechanism is the following: (i) recruits S-adenosyl-L- methionine and cleaves it to generate a 5'-deoxyadenosine radical (5'- dA) in the radical S-adenosyl-L-methionine (rSAM) region, (ii) hydrolyzes acetyl-CoA in the N-acetyltransferase domain and (iii) an acetyl radical is formed by the products of the two domains and (iv) is transferred onto the C5 position of uridine(34) in the bound tRNA molecule. Does not sho [...]
       0.575
MJ_0285
Small heat shock protein (hsp20); Chaperone that confers thermal protection to other proteins; Belongs to the small heat shock protein (HSP20) family.
   
 
 0.565
hisC
Histidinol-phosphate aminotransferase (hisC); Similar to SP:P06986 GB:U02071 GB:X03416 PID:41695 PID:41710 percent identity: 29.00; identified by sequence similarity; putative.
  
  
 0.558
eif5a
Translation initiation factor aIF-5A; Functions by promoting the formation of the first peptide bond; Belongs to the eIF-5A family.
       0.475
dys
Deoxyhypusine synthase (dys1); Catalyzes the NAD-dependent oxidative cleavage of spermidine and the subsequent transfer of the butylamine moiety of spermidine to the epsilon-amino group of a specific lysine residue of the eIF-5A precursor protein to form the intermediate deoxyhypusine residue.
   
   0.474
Your Current Organism:
Methanocaldococcus jannaschii
NCBI taxonomy Id: 243232
Other names: M. jannaschii DSM 2661, Methanocaldococcus jannaschii DSM 2661, Methanocaldococcus jannaschii str. DSM 2661, Methanococcus jannaschii DSM 2661
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