Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
MJ_0971Conserved hypothetical protein; Similar to GP:1707806 percent identity: 29.74; identified by sequence similarity; putative. (365 aa)    
Predicted Functional Partners:
uppS
Conserved hypothetical protein; Catalyzes the sequential condensation of isopentenyl diphosphate (IPP) with geranylgeranyl diphosphate (GGPP) to yield (2Z,6Z,10Z,14Z,18Z,22Z,26Z,30E,34E,38E)-undecaprenyl diphosphate (tritrans,heptacis-UPP). It is probably the precursor of glycosyl carrier lipids.
  
  
 0.787
MJ_0972
Conserved hypothetical protein; Similar to SP:P25743 GB:U00096 PID:1787494 percent identity: 34.00; identified by sequence similarity; putative.
     
 0.785
pyrH
Uridylate kinase (pyrH); Catalyzes the reversible phosphorylation of UMP to UDP.
 
  
 0.710
MJ_1157
Conserved hypothetical protein; Similar to GP:1655726 percent identity: 32.52; identified by sequence similarity; putative; Belongs to the TtcA family.
  
  
 0.701
nusA
Putative transcription termination-antitermination factor (NusA); Participates in transcription termination. Belongs to the NusA family.
 
    0.615
cbiX
Conserved hypothetical protein; Catalyzes the insertion of Co(2+) into sirohydrochlorin as part of the anaerobic pathway to cobalamin biosynthesis. Involved in the biosynthesis of the unique nickel-containing tetrapyrrole coenzyme F430, the prosthetic group of methyl-coenzyme M reductase (MCR), which plays a key role in methanogenesis and anaerobic methane oxidation. Catalyzes the insertion of Ni(2+) into sirohydrochlorin to yield Ni- sirohydrochlorin.
       0.588
hisS
histidyl-tRNA synthetase (hisS); Similar to SP:P30053 percent identity: 35.44; identified by sequence similarity; putative; Belongs to the class-II aminoacyl-tRNA synthetase family.
 
  
 0.585
MJ_0021
Conserved hypothetical protein; Similar to GP:1707810 percent identity: 43.12; identified by sequence similarity; putative.
       0.575
lysS
tRNA synthetase, putative; Similar to GB:D26185 SP:P22250 GB:L14580 GB:M55073 PID:143006 percent identity: 35.54; identified by sequence similarity; putative; Belongs to the class-I aminoacyl-tRNA synthetase family.
 
     0.569
gatA
Amidase; Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu- tRNA(Gln) (By similarity).
  
  
 0.542
Your Current Organism:
Methanocaldococcus jannaschii
NCBI taxonomy Id: 243232
Other names: M. jannaschii DSM 2661, Methanocaldococcus jannaschii DSM 2661, Methanocaldococcus jannaschii str. DSM 2661, Methanococcus jannaschii DSM 2661
Server load: low (16%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.