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STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
MJ_1004Conserved hypothetical protein; Similar to GB:AE000666 percent identity: 48.11; identified by sequence similarity; putative. (214 aa)    
Predicted Functional Partners:
MJ_1005
Hypothetical protein; Identified by GeneMark; putative; M. jannaschii predicted coding region MJ1005.
  
  
 0.968
hacA
3-isopropylmalate dehydratase (leuC); Hydro-lyase with broad substrate specificity for cis- unsaturated tricarboxylic acids. Catalyzes both the reversible dehydration of (R)-homocitrate ((R)-2-hydroxybutane-1,2,4- tricarboxylate) to produce cis-homoaconitate ((Z)-but-1-ene-1,2,4- tricarboxylate), and its hydration to homoisocitrate ((1R,2S)-1- hydroxybutane-1,2,4-tricarboxylate). Is also able to hydrate the analogous longer chain substrates cis-homo(2)-aconitate, cis-homo(3)- aconitate, and even the non-physiological cis-homo(4)-aconitate with similar efficiency. These reactions are pa [...]
       0.851
MJ_1006
Hypothetical protein; Identified by GeneMark; putative; M. jannaschii predicted coding region MJ1006; Belongs to the archaeal ATPase family.
       0.773
MJ_1362
NADH ubiquinone oxidoreductase, subunit 1 isolog; Similar to SP:P03887 percent identity: 24.02; identified by sequence similarity; putative.
 
   
 0.621
valS
valyl-tRNA synthetase (valS); Catalyzes the attachment of valine to tRNA(Val). As ValRS can inadvertently accommodate and process structurally similar amino acids such as threonine, to avoid such errors, it has a 'posttransfer' editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA- dependent manner; Belongs to the class-I aminoacyl-tRNA synthetase family. ValS type 2 subfamily.
       0.523
MJ_0520
NADH-ubiquinone oxidoreductase, subunit 1; Similar to SP:P12772 percent identity: 28.08; identified by sequence similarity; putative; Belongs to the complex I subunit 1 family.
 
   
 0.497
MJ_1303
Polyferredoxin (mvhB); Similar to GB:J04540 PID:149734 GB:AE000666 percent identity: 39.45; identified by sequence similarity; putative.
  
     0.458
dacZ
Conserved hypothetical protein; Diadenylate cyclase that catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP). c-di-AMP is a second messenger for intracellular signal transduction involved in the control of important regulatory processes such as osmoregulation (By similarity).
       0.453
MJ_0138
Cobyric acid synthase (cbiP); Similar to GB:M62866 SP:P29932 PID:151151 percent identity: 33.62; identified by sequence similarity; putative.
  
     0.431
MJ_0760
Conserved hypothetical protein; Similar to SP:P54436 PID:1303708 GB:AL009126 percent identity: 30.26; identified by sequence similarity; putative.
  
     0.421
Your Current Organism:
Methanocaldococcus jannaschii
NCBI taxonomy Id: 243232
Other names: M. jannaschii DSM 2661, Methanocaldococcus jannaschii DSM 2661, Methanocaldococcus jannaschii str. DSM 2661, Methanococcus jannaschii DSM 2661
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