STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
arcSAlignment in; Is responsible for the final step in the biosynthesis of archaeosine, a modified nucleoside present in the dihydrouridine loop (D-loop) of archaeal tRNA. Catalyzes the conversion of 7-cyano-7- deazaguanine (preQ0)-modified tRNA to archaeosine-tRNA, transforming a nitrile group to a formamidine group. Can use either glutamine, asparagine or ammonium as amino donor. (569 aa)    
Predicted Functional Partners:
MJ_1021
Hypothetical protein; Identified by GeneMark; putative; M. jannaschii predicted coding region MJ1021.
  
    0.895
tgtA
Queuine tRNA-ribosyltransferase (tgtA); Exchanges the guanine residue with 7-cyano-7-deazaguanine (preQ0) at position 15 in the dihydrouridine loop (D-loop) of archaeal tRNAs. Can also utilize guanine as substrate.
 
  
0.845
MJ_0550
Conserved hypothetical protein; Similar to GB:AE000666 percent identity: 40.68; identified by sequence similarity; putative.
 
     0.796
rpl40e
LSU ribosomal protein L40E (CEP52); Similar to PIR:B48470 percent identity: 61.11; identified by sequence similarity; putative; Belongs to the eukaryotic ribosomal protein eL40 family.
  
     0.688
MJ_1650
Conserved hypothetical protein; Similar to GB:AE000666 percent identity: 31.03; identified by sequence similarity; putative.
  
     0.674
MJ_1127
Conserved hypothetical protein; Similar to GB:AE000666 percent identity: 46.18; identified by sequence similarity; putative; Belongs to the metallo-dependent hydrolases superfamily.
  
     0.662
MJ_1627
Conserved hypothetical protein; Similar to GP:1669357 percent identity: 35.34; identified by sequence similarity; putative; Belongs to the UPF0179 family.
  
     0.646
MJ_1210
Conserved hypothetical protein; Similar to GB:AE000782 percent identity: 46.03; identified by sequence similarity; putative.
  
     0.636
MJ_0273
Hypothetical protein; Identified by GeneMark; putative; M. jannaschii predicted coding region MJ0273.
  
     0.624
MJ_1545
Conserved hypothetical protein; Similar to GB:AE000782 percent identity: 52.42; identified by sequence similarity; putative.
  
     0.604
Your Current Organism:
Methanocaldococcus jannaschii
NCBI taxonomy Id: 243232
Other names: M. jannaschii DSM 2661, Methanocaldococcus jannaschii DSM 2661, Methanocaldococcus jannaschii str. DSM 2661, Methanococcus jannaschii DSM 2661
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.