Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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Neighborhood
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Co-occurrence
Co-expression
Experiments
Databases
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[Homology]
Score
MJ_1032Conserved hypothetical protein; Similar to GB:AE000782 percent identity: 34.62; identified by sequence similarity; putative. (366 aa)    
Predicted Functional Partners:
srp19
Signal recognition particle, subunit SRP19; Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds directly to 7S RNA and mediates binding of the 54 kDa subunit of the SRP.
       0.907
corA
Magnesium and cobalt transport protein (corA); Mediates influx of magnesium ions. Alternates between open and closed states. Activated by low cytoplasmic Mg(2+) levels. Inactive when cytoplasmic Mg(2+) levels are high. Can also mediate Co(2+) uptake (By similarity). Belongs to the CorA metal ion transporter (MIT) (TC 1.A.35) family.
  
    0.858
MJ_0021
Conserved hypothetical protein; Similar to GP:1707810 percent identity: 43.12; identified by sequence similarity; putative.
 
     0.830
mptE
Conserved hypothetical protein; Catalyzes the transfer of diphosphate from ATP to 6- hydroxymethyl-7,8-dihydropterin (6-HMD), leading to 6-hydroxymethyl- 7,8-dihydropterin diphosphate (6-HMDP); Belongs to the archaeal 6-HMPDK family.
 
     0.753
MJ_0133
Conserved hypothetical protein; Similar to GP:1707762 percent identity: 33.83; identified by sequence similarity; putative.
       0.685
MJ_0810
Conserved hypothetical protein; Similar to GP:949850 percent identity: 33.11; identified by sequence similarity; putative.
       0.685
priS
DNA primase, putative; Catalytic subunit of DNA primase, an RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication. The small subunit contains the primase catalytic core and has DNA synthesis activity on its own. Binding to the large subunit stabilizes and modulates the activity, increasing the rate of DNA synthesis while decreasing the length of the DNA fragments, and conferring RNA synthesis capability. The DNA polymerase activity may enable DNA primase to also catalyze primer extension after primer synthesis. May [...]
  
     0.674
MJ_1052
Conserved hypothetical protein; Similar to PID:1226043 percent identity: 30.85; identified by sequence similarity; putative; Belongs to the UPF0045 family.
       0.657
MJ_1031
Conserved hypothetical protein; Similar to GP:1788715 percent identity: 21.48; identified by sequence similarity; putative.
       0.653
MJ_1545
Conserved hypothetical protein; Similar to GB:AE000782 percent identity: 52.42; identified by sequence similarity; putative.
 
     0.646
Your Current Organism:
Methanocaldococcus jannaschii
NCBI taxonomy Id: 243232
Other names: M. jannaschii DSM 2661, Methanocaldococcus jannaschii DSM 2661, Methanocaldococcus jannaschii str. DSM 2661, Methanococcus jannaschii DSM 2661
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