STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
MJ_1050Conserved hypothetical protein; Broad-specificity nucleoside monophosphate (NMP) kinase that catalyzes the reversible transfer of the terminal phosphate group between nucleoside triphosphates and monophosphates. Belongs to the adenylate kinase family. AK6 subfamily. (177 aa)    
Predicted Functional Partners:
rps11
SSU ribosomal protein S11P (rpsK); Located on the platform of the 30S subunit. Belongs to the universal ribosomal protein uS11 family.
  
 
 0.931
MJ_1049
Hypothetical protein; Identified by GeneMark; putative; M. jannaschii predicted coding region MJ1049.
  
    0.913
hpt
Adenine phosphoribosyltransferase (apt); Catalyzes a salvage reaction resulting in the formation of IMP that is energically less costly than de novo synthesis. Belongs to the purine/pyrimidine phosphoribosyltransferase family. Archaeal HPRT subfamily.
   
 
 0.910
purB
Adenylosuccinate lyase (purB); Similar to GB:J02732 SP:P12047 PID:143366 GB:AL009126 percent identity: 42.51; identified by sequence similarity; putative.
     
 0.902
MJ_1559
Conserved hypothetical protein; Has nucleotide phosphatase activity towards ATP, GTP, CTP, TTP and UTP. May hydrolyze nucleoside diphosphates with lower efficiency (By similarity); Belongs to the THEP1 NTPase family.
     
 0.902
MJ_0108
Pyruvate kinase; Similar to GB:D13095 SP:Q02499 GB:X57859 PID:285623 percent identity: 38.82; identified by sequence similarity; putative.
     
 0.901
adkA
Adenylate kinase (adk); Similar to PID:1086550 PID:1591182 percent identity: 100.00; identified by sequence similarity; putative; Belongs to the archaeal adenylate kinase family.
     
  0.900
surE
surE stationary-phase survival protein SurE; Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates; Belongs to the SurE nucleotidase family.
     
  0.900
ndk
Nucleoside diphosphate kinase, (ndk); Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate; Belongs to the NDK family.
     
 0.900
MJ_0443
Conserved hypothetical protein; Similar to GB:X59720 SP:P25586 PID:5300 percent identity: 27.78; identified by sequence similarity; putative.
  
 
 0.854
Your Current Organism:
Methanocaldococcus jannaschii
NCBI taxonomy Id: 243232
Other names: M. jannaschii DSM 2661, Methanocaldococcus jannaschii DSM 2661, Methanocaldococcus jannaschii str. DSM 2661, Methanococcus jannaschii DSM 2661
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