STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
MJ_1071Hypothetical protein; Identified by GeneMark; putative; M. jannaschii predicted coding region MJ1071; To M.jannaschii MJ0977 C-terminal region. (313 aa)    
Predicted Functional Partners:
MJ_1070
Hypothetical protein; Identified by GeneMark; putative; M. jannaschii predicted coding region MJ1070.
       0.952
MJ_0248
Hypothetical protein; Identified by GeneMark; putative; M. jannaschii predicted coding region MJ0248.
   
 
 0.806
polB
DNA polymerase delta small subunit; Possesses two activities: a DNA synthesis (polymerase) and an exonucleolytic activity that degrades single-stranded DNA in the 3' to 5' direction. Has a template-primer preference which is characteristic of a replicative DNA polymerase (By similarity); Belongs to the DNA polymerase delta/II small subunit family.
    
 
 0.764
topA
DNA topoisomerase I (topA) {Bacillus subtilis; Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA- (5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken stra [...]
   
 
 0.757
MJ_1072
Hypothetical protein; Identified by GeneMark; putative; M. jannaschii predicted coding region MJ1072.
       0.714
tgtA
Queuine tRNA-ribosyltransferase (tgtA); Exchanges the guanine residue with 7-cyano-7-deazaguanine (preQ0) at position 15 in the dihydrouridine loop (D-loop) of archaeal tRNAs. Can also utilize guanine as substrate.
  
    0.604
MJ_1068
Polysaccharide biosynthesis protein (capF) isolog; Similar to GB:U10927 SP:P39855 PID:506702 percent identity: 21.66; identified by sequence similarity; putative.
  
  
 0.565
MJ_1069
Galactosyltransferase isolog; Similar to GP:1486283 percent identity: 26.38; identified by sequence similarity; putative; Belongs to the glycosyltransferase group 1 family. Glycosyltransferase 4 subfamily.
     
 0.536
MJ_1061
Capsular polysaccharide biosynthesis protein D; Similar to GB:U10927 SP:P39853 PID:506700 percent identity: 51.04; identified by sequence similarity; putative; Belongs to the polysaccharide synthase family.
       0.518
MJ_1066
Spore coat polysaccharide biosynthesis protein C (spsC); Similar to GB:X73124 SP:P39623 PID:413989 GB:AL009126 percent identity: 54.97; identified by sequence similarity; putative.
       0.515
Your Current Organism:
Methanocaldococcus jannaschii
NCBI taxonomy Id: 243232
Other names: M. jannaschii DSM 2661, Methanocaldococcus jannaschii DSM 2661, Methanocaldococcus jannaschii str. DSM 2661, Methanococcus jannaschii DSM 2661
Server load: low (38%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.