Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
rio2Conserved hypothetical protein; Similar to SP:P40160 PID:1302211 PID:600058 percent identity: 34.52; identified by sequence similarity; putative; Belongs to the protein kinase superfamily. RIO-type Ser/Thr kinase family. (270 aa)    
Predicted Functional Partners:
nob1
Ribosomal protein S15A isolog; Toxic component of a type II toxin-antitoxin (TA) system. Processes pre-16S-rRNA at its 3' end (the D-site) to yield the mature 3' end (By similarity); Belongs to the PINc/VapC protein family.
   
 0.999
rps6e
SSU ribosomal protein S6E; Similar to SP:P21509 percent identity: 39.84; identified by sequence similarity; putative; Belongs to the eukaryotic ribosomal protein eS6 family.
  
 0.970
rio1
Conserved hypothetical protein; Despite the protein kinase domain is proposed to act predominantly as an ATPase (By similarity).
  
0.968
MJ_0443
Conserved hypothetical protein; Similar to GB:X59720 SP:P25586 PID:5300 percent identity: 27.78; identified by sequence similarity; putative.
   
 
 0.961
rps11
SSU ribosomal protein S11P (rpsK); Located on the platform of the 30S subunit. Belongs to the universal ribosomal protein uS11 family.
  
 0.959
rps5
SSU ribosomal protein S5P (rpsE); With S4 and S12 plays an important role in translational accuracy.
   
 0.955
rps4
SSU ribosomal protein S4P (rpsD); One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit.
   
 0.953
rps3
SSU ribosomal protein S3P (rpsC); Binds the lower part of the 30S subunit head. Belongs to the universal ribosomal protein uS3 family.
   
 0.946
rps15
SSU ribosomal protein S15P (rpsO); Similar to GP:297071 percent identity: 48.34; identified by sequence similarity; putative.
  
 
 0.945
rps3ae
SSU ribosomal protein S3AE; Similar to GP:469248 percent identity: 29.17; identified by sequence similarity; putative; Belongs to the eukaryotic ribosomal protein eS1 family.
  
 0.941
Your Current Organism:
Methanocaldococcus jannaschii
NCBI taxonomy Id: 243232
Other names: M. jannaschii DSM 2661, Methanocaldococcus jannaschii DSM 2661, Methanocaldococcus jannaschii str. DSM 2661, Methanococcus jannaschii DSM 2661
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