Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
cbiNCobalt transport protein (cbiN); Part of the energy-coupling factor (ECF) transporter complex CbiMNOQ involved in cobalt import; Belongs to the CbiN family. (95 aa)    
Predicted Functional Partners:
cbiM
Cobalamin biosynthesis protein (cbiM); Part of the energy-coupling factor (ECF) transporter complex CbiMNOQ involved in cobalt import.
 
 
 0.999
MJ_1089
Cobalt transport protein (cbiQ); Similar to GP:1419077 percent identity: 42.68; identified by sequence similarity; putative.
 
 
 0.998
ecfA
Cobalt transport ATP-binding protein (cbiO); ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates.
 
 
 0.992
MJ_1570
Hypothetical protein; Identified by GeneMark; putative; M. jannaschii predicted coding region MJ1570.
  
 
 0.940
MJ_1569
Cobalamin biosynthesis protein (cbiM); May be involved in metal transport; Belongs to the CbiM family.
  
 
 0.934
MJ_1572
Cobalt transport ATP-binding protein (cbiO); Probably part of an ABC transporter complex. Responsible for energy coupling to the transport system (By similarity).
  
 
 0.923
MJ_1571
Cobalt transport protein (cbiQ); Similar to GP:1419077 percent identity: 27.87; identified by sequence similarity; putative.
  
 
 0.920
cbiL
Cobalamin biosynthesis precorrin-2 methyltransferase (cbiL); Methylates cobalt-precorrin-2 at the C-20 position to produce cobalt-precorrin-3A in the anaerobic cobalamin biosynthesis pathway.
  
  
 0.784
cbiF
Cobalamin biosynthesis precorrin-3 methylase (cbiF); Catalyzes the methylation of C-11 in cobalt-precorrin-4 to form cobalt-precorrin-5A.
  
  
 0.763
cbiE
Cobalamin biosynthesis precorrin-6Y methylase (cbiE); Catalyzes the methylation of C-5 in cobalt-precorrin-7 to form cobalt-precorrin-8.
  
  
 0.758
Your Current Organism:
Methanocaldococcus jannaschii
NCBI taxonomy Id: 243232
Other names: M. jannaschii DSM 2661, Methanocaldococcus jannaschii DSM 2661, Methanocaldococcus jannaschii str. DSM 2661, Methanococcus jannaschii DSM 2661
Server load: low (20%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.