STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
MJ_1094Conserved hypothetical protein; Similar to GP:1439553 percent identity: 30.62; identified by sequence similarity; putative. (385 aa)    
Predicted Functional Partners:
MJ_1384
NADH oxidase; Similar to GB:AE000782 percent identity: 43.64; identified by sequence similarity; putative.
 
  
 0.899
tiaS
Conserved hypothetical protein; ATP-dependent agmatine transferase that catalyzes the formation of 2-agmatinylcytidine (agm2C) at the wobble position (C34) of tRNA(Ile2), converting the codon specificity from AUG to AUA.
       0.871
MJ_1242
Methyl coenzyme M reductase system, component A2 (atwA); Similar to GB:L11748 PID:293151 PID:385924 GB:AE000666 percent identity: 60.26; identified by sequence similarity; putative; Belongs to the ABC transporter superfamily.
 
     0.548
MJ_0921
Conserved hypothetical protein; Similar to GB:AE000666 percent identity: 51.79; identified by sequence similarity; putative.
 
     0.484
cfbD
Vanadium nitrogenase-associated protein N; Involved in the biosynthesis of the unique nickel-containing tetrapyrrole coenzyme F430, the prosthetic group of methyl-coenzyme M reductase (MCR), which plays a key role in methanogenesis and anaerobic methane oxidation. Catalyzes both the six-electron reduction of the tetrahydroporphyrin ring system and the gamma-lactamization of the c- acetamide side chain of Ni-sirohydrochlorin a,c-diamide to yield 15,17(3)-seco-F430-17(3)-acid (seco-F430), the last intermediate in the biosynthesis of the coenzyme F430; Belongs to the NifD/NifK/NifE/NifN family.
  
     0.464
MJ_0611
Conserved hypothetical integral membrane protein; Similar to GP:1565238 percent identity: 34.56; identified by sequence similarity; putative; Belongs to the peptidase M50B family.
 
     0.413
Your Current Organism:
Methanocaldococcus jannaschii
NCBI taxonomy Id: 243232
Other names: M. jannaschii DSM 2661, Methanocaldococcus jannaschii DSM 2661, Methanocaldococcus jannaschii str. DSM 2661, Methanococcus jannaschii DSM 2661
Server load: low (22%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.