STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
relE3Conserved hypothetical protein; Toxic component of a type II toxin-antitoxin (TA) system. Has RNase activity (By similarity). Is very toxic upon expression in E.coli. Its toxic activity is probably neutralized by the cognate antitoxin RelB3. (88 aa)    
Predicted Functional Partners:
relB4
Hypothetical protein; Antitoxin component of a type II toxin-antitoxin (TA) system. Its cognate toxin is RelE4 (Potential).
  
  
 0.986
relB1
Hypothetical protein; Antitoxin component of a type II toxin-antitoxin (TA) system. Its cognate toxin is RelE1 (Potential).
   
 
 0.975
relE1
Conserved hypothetical protein; Toxic component of a type II toxin-antitoxin (TA) system. Its cognate antitoxin is RelB1 (Potential).
      
 0.861
vapC3
Virulence associated protein C (vapC); Toxic component of a type II toxin-antitoxin (TA) system. An RNase. Its cognate antitoxin is VapB3 (By similarity); Belongs to the PINc/VapC protein family.
     
 0.723
vapB3
Conserved hypothetical protein; Possibly the antitoxin component of a type II toxin-antitoxin (TA) system. Its cognate toxin is VapC3 (Potential).
      
 0.640
MJ_1680
Conserved hypothetical protein; Similar to GP:1653165 percent identity: 30.83; identified by sequence similarity; putative.
 
   
 0.584
trkA
TRK system potassium uptake protein (trkA); Part of a potassium transport system.
     
 0.474
thrB
Homoserine kinase (thrB); Catalyzes the ATP-dependent phosphorylation of L-homoserine to L-homoserine phosphate; Belongs to the GHMP kinase family. Homoserine kinase subfamily.
       0.441
Your Current Organism:
Methanocaldococcus jannaschii
NCBI taxonomy Id: 243232
Other names: M. jannaschii DSM 2661, Methanocaldococcus jannaschii DSM 2661, Methanocaldococcus jannaschii str. DSM 2661, Methanococcus jannaschii DSM 2661
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