STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ccatRNA nucleotidyltransferase (cca); Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate; Belongs to the tRNA nucleotidyltransferase/poly(A) polymerase family. Archaeal CCA-adding enzyme subfamily. (449 aa)    
Predicted Functional Partners:
MJ_1110
Conserved hypothetical protein; Similar to GB:AE000666 percent identity: 30.00; identified by sequence similarity; putative.
  
    0.936
MJ_1113
N-acetylglucosamine-1-phosphate transferase; Similar to GB:D28748 SP:P39465 PID:506372 percent identity: 28.00; identified by sequence similarity; putative.
       0.751
hmd
H2-forming N5,N10-methylene-tetrahydromethanopterin dehydrogenease (hmd); Catalyzes the reversible reduction of methenyl-H(4)MPT(+) to methylene-H(4)MPT.
      
 0.720
nac
Conserved hypothetical protein; Contacts the emerging nascent chain on the ribosome. Belongs to the NAC-alpha family.
 
     0.681
MJ_0038
Conserved hypothetical protein; Similar to GB:AE000666 percent identity: 51.12; identified by sequence similarity; putative.
 
   
 0.660
MJ_0715
H2-forming N5,N10-methylene-tetrahydromethanopterin dehydrogenase-related protein (hmd); Similar to PID:1149527 SP:Q50840 percent identity: 29.86; identified by sequence similarity; putative; Belongs to the HMD family.
     
 0.649
dnaG
Conserved hypothetical protein; RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication.
 
   
 0.636
MJ_1399
Alignment in; Identified by sequence similarity; putative; Belongs to the UPF0200 family.
 
     0.612
pfdB
erpK protein isolog; Molecular chaperone capable of stabilizing a range of proteins. Seems to fulfill an ATP-independent, HSP70-like function in archaeal de novo protein folding (By similarity).
  
     0.597
MJ_1533
Conserved hypothetical protein; Similar to GB:X04021 PID:44719 PID:44720 percent identity: 67.05; identified by sequence similarity; putative.
  
   
 0.586
Your Current Organism:
Methanocaldococcus jannaschii
NCBI taxonomy Id: 243232
Other names: M. jannaschii DSM 2661, Methanocaldococcus jannaschii DSM 2661, Methanocaldococcus jannaschii str. DSM 2661, Methanococcus jannaschii DSM 2661
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