STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
vapC3Virulence associated protein C (vapC); Toxic component of a type II toxin-antitoxin (TA) system. An RNase. Its cognate antitoxin is VapB3 (By similarity); Belongs to the PINc/VapC protein family. (94 aa)    
Predicted Functional Partners:
vapB3
Conserved hypothetical protein; Possibly the antitoxin component of a type II toxin-antitoxin (TA) system. Its cognate toxin is VapC3 (Potential).
     
 0.975
vapC2
Conserved hypothetical protein; Toxic component of a type II toxin-antitoxin (TA) system. An RNase. Its cognate antitoxin is VapB2 (By similarity). Belongs to the PINc/VapC protein family.
     
 0.881
vapB2
Hypothetical protein; Possibly the antitoxin component of a type II toxin-antitoxin (TA) system. Its cognate toxin is VapC2 (Potential).
     
 0.872
relE3
Conserved hypothetical protein; Toxic component of a type II toxin-antitoxin (TA) system. Has RNase activity (By similarity). Is very toxic upon expression in E.coli. Its toxic activity is probably neutralized by the cognate antitoxin RelB3.
     
 0.723
vapC4
Conserved hypothetical protein; Toxic component of a type II toxin-antitoxin (TA) system. An RNase. Its cognate antitoxin is VapB4 (By similarity). Belongs to the PINc/VapC protein family.
      
 0.640
MJ_1123
Conserved hypothetical protein; Similar to SP:Q10853 PID:1403450 percent identity: 34.00; identified by sequence similarity; putative; To M.jannaschii MJ0638 and MJ1252 and M.tuberculosis Rv2003c.
       0.554
hel308
Putative SKI2-family helicase; DNA-dependent ATPase and 3'-5' DNA helicase that may be involved in repair of stalled replication forks; Belongs to the helicase family. Hel308 subfamily.
       0.530
Your Current Organism:
Methanocaldococcus jannaschii
NCBI taxonomy Id: 243232
Other names: M. jannaschii DSM 2661, Methanocaldococcus jannaschii DSM 2661, Methanocaldococcus jannaschii str. DSM 2661, Methanococcus jannaschii DSM 2661
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