STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
hel308Putative SKI2-family helicase; DNA-dependent ATPase and 3'-5' DNA helicase that may be involved in repair of stalled replication forks; Belongs to the helicase family. Hel308 subfamily. (1195 aa)    
Predicted Functional Partners:
rpl7ae
LSU ribosomal protein L7AE; Multifunctional RNA-binding protein that recognizes the K- turn motif in ribosomal RNA, the RNA component of RNase P, box H/ACA, box C/D and box C'/D' sRNAs; Belongs to the eukaryotic ribosomal protein eL8 family.
 
 0.999
fusA
Translation elongation factor EF-2; Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post-translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome (By similarity); Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase [...]
 
 0.998
MJ_1123
Conserved hypothetical protein; Similar to SP:Q10853 PID:1403450 percent identity: 34.00; identified by sequence similarity; putative; To M.jannaschii MJ0638 and MJ1252 and M.tuberculosis Rv2003c.
     
 0.914
MJ_0669
ATP-dependent RNA helicase, DEAD-family (deaD); Similar to GB:L42023 SP:P44586 PID:1003361 PID:1222156 PID:1204489 percent identity: 43.17; identified by sequence similarity; putative; Belongs to the DEAD box helicase family.
   
 0.890
flpA
Fibrillarin (fib); Involved in pre-rRNA and tRNA processing. Utilizes the methyl donor S-adenosyl-L-methionine to catalyze the site-specific 2'-hydroxyl methylation of ribose moieties in rRNA and tRNA. Site specificity is provided by a guide RNA that base pairs with the substrate. Methylation occurs at a characteristic distance from the sequence involved in base pairing with the guide RNA.
   
 0.890
MJ_1519
Exodeoxyribonuclease V (recD); Similar to GB:L42023 SP:P45158 PID:1007312 PID:1205560 PID:1221454 percent identity: 33.33; identified by sequence similarity; putative.
   
 0.890
rps3
SSU ribosomal protein S3P (rpsC); Binds the lower part of the 30S subunit head. Belongs to the universal ribosomal protein uS3 family.
   
 
 0.834
rps6e
SSU ribosomal protein S6E; Similar to SP:P21509 percent identity: 39.84; identified by sequence similarity; putative; Belongs to the eukaryotic ribosomal protein eS6 family.
 
   0.807
rps8e
SSU ribosomal protein S8E; Similar to SP:P49402 percent identity: 50.00; identified by sequence similarity; putative.
 
 
 
 0.803
bioF
8-amino-7-oxononanoate synthase (bioF); Catalyzes the decarboxylative condensation of pimeloyl-[acyl- carrier protein] and L-alanine to produce 8-amino-7-oxononanoate (AON), [acyl-carrier protein], and carbon dioxide.
  
    0.802
Your Current Organism:
Methanocaldococcus jannaschii
NCBI taxonomy Id: 243232
Other names: M. jannaschii DSM 2661, Methanocaldococcus jannaschii DSM 2661, Methanocaldococcus jannaschii str. DSM 2661, Methanococcus jannaschii DSM 2661
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