Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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Co-occurrence
Co-expression
Experiments
Databases
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[Homology]
Score
MJ_1127Conserved hypothetical protein; Similar to GB:AE000666 percent identity: 46.18; identified by sequence similarity; putative; Belongs to the metallo-dependent hydrolases superfamily. (280 aa)    
Predicted Functional Partners:
rpl40e
LSU ribosomal protein L40E (CEP52); Similar to PIR:B48470 percent identity: 61.11; identified by sequence similarity; putative; Belongs to the eukaryotic ribosomal protein eL40 family.
 
     0.699
MJ_1650
Conserved hypothetical protein; Similar to GB:AE000666 percent identity: 31.03; identified by sequence similarity; putative.
 
     0.672
mptD
Conserved hypothetical protein; Catalyzes the conversion of 7,8-dihydroneopterin (H2Neo) to 6-hydroxymethyl-7,8-dihydropterin (6-HMD).
 
     0.669
arcS
Alignment in; Is responsible for the final step in the biosynthesis of archaeosine, a modified nucleoside present in the dihydrouridine loop (D-loop) of archaeal tRNA. Catalyzes the conversion of 7-cyano-7- deazaguanine (preQ0)-modified tRNA to archaeosine-tRNA, transforming a nitrile group to a formamidine group. Can use either glutamine, asparagine or ammonium as amino donor.
  
     0.662
hflX
GTP-binding protein, member of GTP1/OBG-family; GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis. Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. HflX GTPase family.
       0.600
MJ_1627
Conserved hypothetical protein; Similar to GP:1669357 percent identity: 35.34; identified by sequence similarity; putative; Belongs to the UPF0179 family.
  
     0.546
MJ_1545
Conserved hypothetical protein; Similar to GB:AE000782 percent identity: 52.42; identified by sequence similarity; putative.
  
     0.542
MJ_0550
Conserved hypothetical protein; Similar to GB:AE000666 percent identity: 40.68; identified by sequence similarity; putative.
  
     0.539
rnz
Conserved hypothetical protein; Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA; Belongs to the RNase Z family.
      
 0.511
MJ_0482
Conserved hypothetical protein; Similar to GB:AE000666 percent identity: 60.00; identified by sequence similarity; putative.
 
     0.493
Your Current Organism:
Methanocaldococcus jannaschii
NCBI taxonomy Id: 243232
Other names: M. jannaschii DSM 2661, Methanocaldococcus jannaschii DSM 2661, Methanocaldococcus jannaschii str. DSM 2661, Methanococcus jannaschii DSM 2661
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