STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
MJ_1129Conserved hypothetical protein; Similar to GP:1620928 percent identity: 33.33; identified by sequence similarity; putative. (95 aa)    
Predicted Functional Partners:
MJ_1130
O-sialoglycoprotein endopeptidase (gcp); Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is a component of the KEOPS complex that is probably involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37. The Kae1 domain likely plays a direct catalytic role in this reaction (By similarity). The Bud32 domain probably displays kinase activity that regulates Kae1 function. In vitro, exhibits low ATPase activity, but does not bind DNA and does [...]
       0.787
MJ_1128
Conserved hypothetical protein; Similar to SP:P46555 percent identity: 32.32; identified by sequence similarity; putative.
       0.778
MJ_0035
ABC transporter subunit; Similar to SP:P48255 percent identity: 37.61; identified by sequence similarity; putative; Belongs to the ABC transporter superfamily.
 
  
 0.695
tgtA
Queuine tRNA-ribosyltransferase (tgtA); Exchanges the guanine residue with 7-cyano-7-deazaguanine (preQ0) at position 15 in the dihydrouridine loop (D-loop) of archaeal tRNAs. Can also utilize guanine as substrate.
       0.571
MJ_0034
Conserved hypothetical protein; Similar to PID:726070 GB:AE000666 percent identity: 23.57; identified by sequence similarity; putative; Belongs to the UPF0051 (ycf24) family.
     
 0.561
MJ_0304
Ferripyochelin binding protein (fbp); Similar to GB:M82832 SP:P40882 PID:151224 percent identity: 52.82; identified by sequence similarity; putative; Belongs to the gamma-class carbonic anhydrase family.
     
 0.552
MJ_0867
Conserved hypothetical protein; Catalyzes the methylthiolation of N6- threonylcarbamoyladenosine (t(6)A), leading to the formation of 2- methylthio-N6-threonylcarbamoyladenosine (ms(2)t(6)A) at position 37 in tRNAs that read codons beginning with adenine.
      
 0.459
rnhB
Ribonuclease HII (rnhB); Endonuclease that specifically degrades the RNA of RNA-DNA hybrids; Belongs to the RNase HII family.
       0.431
MJ_0928
Protoporphyrinogen oxidase (hemK); Putative protein methyltransferase using S-adenosyl-L- methionine as the methyl donor. May methylate a Gln residue in target proteins (By similarity); Belongs to the eukaryotic/archaeal PrmC-related family.
       0.431
MJ_0990
Conserved hypothetical protein; Similar to GB:L13279 SP:P31065 PID:290415 GB:U00096 PID:1788239 percent identity: 39.13; identified by sequence similarity; putative; Belongs to the sulfur carrier protein TusA family.
       0.431
Your Current Organism:
Methanocaldococcus jannaschii
NCBI taxonomy Id: 243232
Other names: M. jannaschii DSM 2661, Methanocaldococcus jannaschii DSM 2661, Methanocaldococcus jannaschii str. DSM 2661, Methanococcus jannaschii DSM 2661
Server load: low (20%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.