Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
MJ_1134Conserved hypothetical protein; Similar to GB:L09228 SP:P35154 PID:410131 GB:AL009126 percent identity: 21.63; identified by sequence similarity; putative. (226 aa)    
Predicted Functional Partners:
smc
Chromosome segretation protein (smc1); Required for chromosome condensation and partitioning. Belongs to the SMC family.
 
 
 0.971
moaC
Molybdenum cofactor biosynthesis protein (moaC); Catalyzes the conversion of (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate to cyclic pyranopterin monophosphate (cPMP); Belongs to the MoaC family.
       0.794
rad50
Purine NTPase; Part of the Rad50/Mre11 complex, which is involved in the early steps of DNA double-strand break (DSB) repair. The complex may facilitate opening of the processed DNA ends to aid in the recruitment of HerA and NurA. Rad50 controls the balance between DNA end bridging and DNA resection via ATP-dependent structural rearrangements of the Rad50/Mre11 complex; Belongs to the SMC family. RAD50 subfamily.
 
   
 0.705
MJ_0611
Conserved hypothetical integral membrane protein; Similar to GP:1565238 percent identity: 34.56; identified by sequence similarity; putative; Belongs to the peptidase M50B family.
       0.699
gatB
Glu-tRNA amidotransferase (gatB); Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl- tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp- tRNA(Asn) or phospho-Glu-tRNA(Gln) (By similarity); Belongs to the GatB/GatE family. GatB subfamily.
 
   
 0.684
MJ_1079
Conserved hypothetical protein; Similar to GB:AE000666 percent identity: 30.75; identified by sequence similarity; putative.
  
     0.620
rps8e
SSU ribosomal protein S8E; Similar to SP:P49402 percent identity: 50.00; identified by sequence similarity; putative.
       0.575
MJ_0786
Hypothetical protein; Identified by GeneMark; putative; M. jannaschii predicted coding region MJ0786.
       0.575
MJ_0971
Conserved hypothetical protein; Similar to GP:1707806 percent identity: 29.74; identified by sequence similarity; putative.
 
  
 0.528
MJ_0039
Conserved hypothetical protein; Similar to GB:AE000666 percent identity: 44.44; identified by sequence similarity; putative.
  
     0.522
Your Current Organism:
Methanocaldococcus jannaschii
NCBI taxonomy Id: 243232
Other names: M. jannaschii DSM 2661, Methanocaldococcus jannaschii DSM 2661, Methanocaldococcus jannaschii str. DSM 2661, Methanococcus jannaschii DSM 2661
Server load: low (12%) [HD]