node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
MJ_0206 | comB | MJ_0206 | MJ_1140 | Conserved hypothetical protein; Similar to GB:AE000782 percent identity: 50.38; identified by sequence similarity; putative. | Conserved hypothetical protein; Hydrolyzes both enantiomers of 2-phosphosulfolactate. Able to hydrolyze both enantiomers of 2-hydroxycarboxylic acids with pseudosymmetric centers of inversion. Specifically hydrolyzes (S)- phospholactate and (S)-phosphoglycerate. | 0.843 |
MJ_0670 | comB | MJ_0670 | MJ_1140 | Conserved hypothetical protein; Similar to GB:AE000666 percent identity: 37.37; identified by sequence similarity; putative. | Conserved hypothetical protein; Hydrolyzes both enantiomers of 2-phosphosulfolactate. Able to hydrolyze both enantiomers of 2-hydroxycarboxylic acids with pseudosymmetric centers of inversion. Specifically hydrolyzes (S)- phospholactate and (S)-phosphoglycerate. | 0.529 |
MJ_1141 | MJ_1142 | MJ_1141 | MJ_1142 | Conserved hypothetical protein; Similar to GB:AE000666 percent identity: 38.92; identified by sequence similarity; putative. | Arsenical pump-driving ATPase (arsA); Anion-transporting ATPase. Catalyzes the extrusion of arsenite (By similarity). | 0.988 |
MJ_1141 | MJ_1143 | MJ_1141 | MJ_1143 | Conserved hypothetical protein; Similar to GB:AE000666 percent identity: 38.92; identified by sequence similarity; putative. | Conserved hypothetical protein; Large-conductance mechanosensitive channel that opens in response to stretch forces in the membrane lipid bilayer. Selective for cations. Rectifies with voltage; Belongs to the MscS (TC 1.A.23) family. | 0.595 |
MJ_1141 | comB | MJ_1141 | MJ_1140 | Conserved hypothetical protein; Similar to GB:AE000666 percent identity: 38.92; identified by sequence similarity; putative. | Conserved hypothetical protein; Hydrolyzes both enantiomers of 2-phosphosulfolactate. Able to hydrolyze both enantiomers of 2-hydroxycarboxylic acids with pseudosymmetric centers of inversion. Specifically hydrolyzes (S)- phospholactate and (S)-phosphoglycerate. | 0.626 |
MJ_1141 | rnp3 | MJ_1141 | MJ_1139 | Conserved hypothetical protein; Similar to GB:AE000666 percent identity: 38.92; identified by sequence similarity; putative. | Hypothetical protein; Part of ribonuclease P, a protein complex that generates mature tRNA molecules by cleaving their 5'-ends. Belongs to the eukaryotic/archaeal RNase P protein component 3 family. | 0.568 |
MJ_1142 | MJ_1141 | MJ_1142 | MJ_1141 | Arsenical pump-driving ATPase (arsA); Anion-transporting ATPase. Catalyzes the extrusion of arsenite (By similarity). | Conserved hypothetical protein; Similar to GB:AE000666 percent identity: 38.92; identified by sequence similarity; putative. | 0.988 |
MJ_1142 | MJ_1143 | MJ_1142 | MJ_1143 | Arsenical pump-driving ATPase (arsA); Anion-transporting ATPase. Catalyzes the extrusion of arsenite (By similarity). | Conserved hypothetical protein; Large-conductance mechanosensitive channel that opens in response to stretch forces in the membrane lipid bilayer. Selective for cations. Rectifies with voltage; Belongs to the MscS (TC 1.A.23) family. | 0.645 |
MJ_1142 | comB | MJ_1142 | MJ_1140 | Arsenical pump-driving ATPase (arsA); Anion-transporting ATPase. Catalyzes the extrusion of arsenite (By similarity). | Conserved hypothetical protein; Hydrolyzes both enantiomers of 2-phosphosulfolactate. Able to hydrolyze both enantiomers of 2-hydroxycarboxylic acids with pseudosymmetric centers of inversion. Specifically hydrolyzes (S)- phospholactate and (S)-phosphoglycerate. | 0.543 |
MJ_1142 | rnp3 | MJ_1142 | MJ_1139 | Arsenical pump-driving ATPase (arsA); Anion-transporting ATPase. Catalyzes the extrusion of arsenite (By similarity). | Hypothetical protein; Part of ribonuclease P, a protein complex that generates mature tRNA molecules by cleaving their 5'-ends. Belongs to the eukaryotic/archaeal RNase P protein component 3 family. | 0.512 |
MJ_1143 | MJ_1141 | MJ_1143 | MJ_1141 | Conserved hypothetical protein; Large-conductance mechanosensitive channel that opens in response to stretch forces in the membrane lipid bilayer. Selective for cations. Rectifies with voltage; Belongs to the MscS (TC 1.A.23) family. | Conserved hypothetical protein; Similar to GB:AE000666 percent identity: 38.92; identified by sequence similarity; putative. | 0.595 |
MJ_1143 | MJ_1142 | MJ_1143 | MJ_1142 | Conserved hypothetical protein; Large-conductance mechanosensitive channel that opens in response to stretch forces in the membrane lipid bilayer. Selective for cations. Rectifies with voltage; Belongs to the MscS (TC 1.A.23) family. | Arsenical pump-driving ATPase (arsA); Anion-transporting ATPase. Catalyzes the extrusion of arsenite (By similarity). | 0.645 |
MJ_1143 | comB | MJ_1143 | MJ_1140 | Conserved hypothetical protein; Large-conductance mechanosensitive channel that opens in response to stretch forces in the membrane lipid bilayer. Selective for cations. Rectifies with voltage; Belongs to the MscS (TC 1.A.23) family. | Conserved hypothetical protein; Hydrolyzes both enantiomers of 2-phosphosulfolactate. Able to hydrolyze both enantiomers of 2-hydroxycarboxylic acids with pseudosymmetric centers of inversion. Specifically hydrolyzes (S)- phospholactate and (S)-phosphoglycerate. | 0.442 |
MJ_1143 | rnp3 | MJ_1143 | MJ_1139 | Conserved hypothetical protein; Large-conductance mechanosensitive channel that opens in response to stretch forces in the membrane lipid bilayer. Selective for cations. Rectifies with voltage; Belongs to the MscS (TC 1.A.23) family. | Hypothetical protein; Part of ribonuclease P, a protein complex that generates mature tRNA molecules by cleaving their 5'-ends. Belongs to the eukaryotic/archaeal RNase P protein component 3 family. | 0.429 |
MJ_1157 | comB | MJ_1157 | MJ_1140 | Conserved hypothetical protein; Similar to GP:1655726 percent identity: 32.52; identified by sequence similarity; putative; Belongs to the TtcA family. | Conserved hypothetical protein; Hydrolyzes both enantiomers of 2-phosphosulfolactate. Able to hydrolyze both enantiomers of 2-hydroxycarboxylic acids with pseudosymmetric centers of inversion. Specifically hydrolyzes (S)- phospholactate and (S)-phosphoglycerate. | 0.882 |
comA | comB | MJ_0255 | MJ_1140 | Conserved hypothetical protein; Catalyzes the addition of sulfite to phosphoenolpyruvate (PEP) to yield (2R)-phospho-3-sulfolactate (PSL). | Conserved hypothetical protein; Hydrolyzes both enantiomers of 2-phosphosulfolactate. Able to hydrolyze both enantiomers of 2-hydroxycarboxylic acids with pseudosymmetric centers of inversion. Specifically hydrolyzes (S)- phospholactate and (S)-phosphoglycerate. | 0.998 |
comA | comC | MJ_0255 | MJ_1425 | Conserved hypothetical protein; Catalyzes the addition of sulfite to phosphoenolpyruvate (PEP) to yield (2R)-phospho-3-sulfolactate (PSL). | Malate dehydrogenase; Catalyzes the reduction of sulfopyruvate to (R)-sulfolactate much more efficiently than the reverse reaction. Also catalyzes the reduction of oxaloacetate, alpha-ketoglutarate, and to a much lower extent, KHTCA, but not pyruvate. Involved in the biosynthesis of both coenzyme M (with (R)-sulfolactate) and methanopterin (with alpha- ketoglutarate). | 0.895 |
comA | mdh | MJ_0255 | MJ_0490 | Conserved hypothetical protein; Catalyzes the addition of sulfite to phosphoenolpyruvate (PEP) to yield (2R)-phospho-3-sulfolactate (PSL). | L-lactate dehydrogenase EGAD|7256|705; Catalyzes the reversible oxidation of (S)-malate and (S)- sulfolactate to oxaloacetate and sulfopyruvate, respectively. Can use both NADH and NADPH, although activity is higher with NADPH. Oxidation of (S)-sulfolactate is observed only in the presence of NADP(+). Can also oxidize tartrate. Cannot reduce pyruvate, nor alpha-ketoglutarate. Belongs to the LDH/MDH superfamily. | 0.640 |
comB | MJ_0206 | MJ_1140 | MJ_0206 | Conserved hypothetical protein; Hydrolyzes both enantiomers of 2-phosphosulfolactate. Able to hydrolyze both enantiomers of 2-hydroxycarboxylic acids with pseudosymmetric centers of inversion. Specifically hydrolyzes (S)- phospholactate and (S)-phosphoglycerate. | Conserved hypothetical protein; Similar to GB:AE000782 percent identity: 50.38; identified by sequence similarity; putative. | 0.843 |
comB | MJ_0670 | MJ_1140 | MJ_0670 | Conserved hypothetical protein; Hydrolyzes both enantiomers of 2-phosphosulfolactate. Able to hydrolyze both enantiomers of 2-hydroxycarboxylic acids with pseudosymmetric centers of inversion. Specifically hydrolyzes (S)- phospholactate and (S)-phosphoglycerate. | Conserved hypothetical protein; Similar to GB:AE000666 percent identity: 37.37; identified by sequence similarity; putative. | 0.529 |