Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
MJ_1143Conserved hypothetical protein; Large-conductance mechanosensitive channel that opens in response to stretch forces in the membrane lipid bilayer. Selective for cations. Rectifies with voltage; Belongs to the MscS (TC 1.A.23) family. (361 aa)    
Predicted Functional Partners:
MJ_1650
Conserved hypothetical protein; Similar to GB:AE000666 percent identity: 31.03; identified by sequence similarity; putative.
  
    0.665
MJ_1142
Arsenical pump-driving ATPase (arsA); Anion-transporting ATPase. Catalyzes the extrusion of arsenite (By similarity).
     
 0.663
MJ_1141
Conserved hypothetical protein; Similar to GB:AE000666 percent identity: 38.92; identified by sequence similarity; putative.
       0.596
comB
Conserved hypothetical protein; Hydrolyzes both enantiomers of 2-phosphosulfolactate. Able to hydrolyze both enantiomers of 2-hydroxycarboxylic acids with pseudosymmetric centers of inversion. Specifically hydrolyzes (S)- phospholactate and (S)-phosphoglycerate.
       0.442
rnp3
Hypothetical protein; Part of ribonuclease P, a protein complex that generates mature tRNA molecules by cleaving their 5'-ends. Belongs to the eukaryotic/archaeal RNase P protein component 3 family.
       0.429
Your Current Organism:
Methanocaldococcus jannaschii
NCBI taxonomy Id: 243232
Other names: M. jannaschii DSM 2661, Methanocaldococcus jannaschii DSM 2661, Methanocaldococcus jannaschii str. DSM 2661, Methanococcus jannaschii DSM 2661
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