Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
MJ_1154Conserved hypothetical protein; Similar to GP:1561567 percent identity: 32.98; identified by sequence similarity; putative. (451 aa)    
Predicted Functional Partners:
MJ_0699
Atrazine chlorohydrolase isolog; Similar to GP:1493840 percent identity: 28.15; identified by sequence similarity; putative; Belongs to the metallo-dependent hydrolases superfamily.
     
 0.708
ubiX
Phenylacrylic acid decarboxylase; Flavin prenyltransferase that catalyzes the synthesis of the prenylated FMN cofactor (prenyl-FMN) for 4-hydroxy-3-polyprenylbenzoic acid decarboxylase UbiD. The prenyltransferase is metal-independent and links a dimethylallyl moiety from dimethylallyl monophosphate (DMAP) to the flavin N5 and C6 atoms of FMN; Belongs to the UbiX/PAD1 family.
  
    0.707
cofD
Conserved hypothetical protein; Catalyzes the transfer of the phosphoenolpyruvate moiety from enoylpyruvoyl-2-diphospho-5'-guanosine (EPPG) to 7,8-didemethyl-8- hydroxy-5-deazariboflavin (FO) with the formation of dehydro coenzyme F420-0 and GMP.
       0.685
MJ_0227
Conserved hypothetical protein; Similar to GB:AE000666 percent identity: 40.07; identified by sequence similarity; putative.
       0.676
MJ_0144
Conserved hypothetical protein; Similar to GB:S61233 PID:385923 GB:AE000666 percent identity: 36.10; identified by sequence similarity; putative.
     
 0.663
MJ_1453
Hypothetical protein; Identified by GeneMark; putative; M. jannaschii predicted coding region MJ1453; To M.thermoautotrophicum MTH863.
       0.662
fusA
Translation elongation factor EF-2; Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post-translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome (By similarity); Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase [...]
     
 0.648
pyrH
Uridylate kinase (pyrH); Catalyzes the reversible phosphorylation of UMP to UDP.
 
     0.628
MJ_1133
Conserved hypothetical protein; Similar to SP:P22349 GB:X02586 PID:44543 percent identity: 45.85; identified by sequence similarity; putative; Belongs to the UbiD family.
       0.627
MJ_1313
Conserved hypothetical protein; Similar to GB:AE000666 percent identity: 55.44; identified by sequence similarity; putative; To M.thermoautotrophicum MTH1421.
       0.611
Your Current Organism:
Methanocaldococcus jannaschii
NCBI taxonomy Id: 243232
Other names: M. jannaschii DSM 2661, Methanocaldococcus jannaschii DSM 2661, Methanocaldococcus jannaschii str. DSM 2661, Methanococcus jannaschii DSM 2661
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