Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
fwdGFormylmethanofuran dehydrogenase, subunit G (tungsten) (fwdG); Similar to PID:871460 GB:AE000666 PID:1890208 percent identity: 59.74; identified by sequence similarity; putative. (82 aa)    
Predicted Functional Partners:
fwdF
Formylmethanofuran dehydrogenase, subunit F (tungsten) (fwdF); Similar to PID:871459 GB:AE000666 PID:1890207 percent identity: 48.34; identified by sequence similarity; putative.
  
 
 0.999
fwdD
Formylmethanofuran dehydrogenase, subunit D (tungsten) (fwdD); Similar to PID:871461 GB:AE000666 PID:1890209 percent identity: 58.54; identified by sequence similarity; putative.
  
 0.999
fwdE
Formylmethanofuran dehydrogenase, subunit E (tungsten) (fwdE); Similar to PID:871458 GB:AE000666 PID:1890206 percent identity: 41.22; identified by sequence similarity; putative.
  
 
 0.998
fwdA
Formylmethanofuran dehydrogenase, subunit A (tungsten) (fwdA); Similar to PID:871462 GB:AE000666 PID:1890210 percent identity: 68.95; identified by sequence similarity; putative; Belongs to the metallo-dependent hydrolases superfamily. FwdA/FmdA family.
  
  0.998
fwdC
Formylmethanofuran dehydrogenase, subunit C (tungsten) (fwdC); Catalyzes the reversible oxidation of CO(2) and methanofuran (MFR) to N-formylmethanofuran (CHO-MFR). This enzyme is oxygen-labile. Belongs to the FwdC/FmdC family.
  
 
  0.990
fdhB
Formate dehydrogenase, beta subunit; Catalyzes the oxidation of formate; Belongs to the FrhB family.
   
  0.970
MJ_0006
Formate dehydrogenase, alpha subunit; Similar to GB:J02581 SP:P06131 PID:149708 percent identity: 41.56; identified by sequence similarity; putative; Belongs to the prokaryotic molybdopterin-containing oxidoreductase family.
   
  0.964
ftr
Formylmethanofuran:tetrahydromethanopterin formyltransferase (ftr); Catalyzes the reversible transfer of a formyl group from formylmethanofuran (formyl-MFR) to tetrahydromethanopterin (H(4)MPT) so as to produce 5-formyl tetrahydromethanopterin (5-formyl-H(4)MPT) and methanofuran (MFR); Belongs to the FTR family.
    
 0.910
hdrB1
Heterodisulfide reductase, subunit B1 (hdrB1); Part of a complex that catalyzes the reversible reduction of CoM-S-S-CoB to the thiol-coenzymes H-S-CoM (coenzyme M) and H-S-CoB (coenzyme B).
   
 
 0.787
hdrB2
Heterodisulfide reductase, subunit B2 (hdrB2); Part of a complex that catalyzes the reversible reduction of CoM-S-S-CoB to the thiol-coenzymes H-S-CoM (coenzyme M) and H-S-CoB (coenzyme B).
   
 
 0.787
Your Current Organism:
Methanocaldococcus jannaschii
NCBI taxonomy Id: 243232
Other names: M. jannaschii DSM 2661, Methanocaldococcus jannaschii DSM 2661, Methanocaldococcus jannaschii str. DSM 2661, Methanococcus jannaschii DSM 2661
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