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STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
MJ_1177Conserved hypothetical protein; Similar to GB:M94110 SP:Q04454 PID:142791 percent identity: 24.44; identified by sequence similarity; putative. (334 aa)    
Predicted Functional Partners:
ribL
Glycerol-3-phosphate cytidyltransferase (taqD); Catalyzes the transfer of the AMP portion of ATP to flavin mononucleotide (FMN) to produce flavin adenine dinucleotide (FAD) coenzyme. To a lesser extent, is also able to utilize other nucleotides such as CTP and GTP as substrates, producing the modified coenzymes, flavin cytosine dinucleotide (FCD) and flavin guanine dinucleotide (FGD), respectively. Does not catalyze the reverse reaction to produce FMN and ATP from FAD and PPi. Does not function as a glycerol-3- phosphate cytidylyltransferase, as previously annotated in the complete gen [...]
       0.875
MJ_1178
Conserved hypothetical protein; Similar to SP:P42982 PID:755606 PID:1146237 GB:AL009126 percent identity: 26.36; identified by sequence similarity; putative; Belongs to the glycosyltransferase group 1 family. Glycosyltransferase 4 subfamily.
 
  
 0.659
MJ_0651
Protease IV (sppA); Similar to GB:L42023 SP:P45243 PID:1007737 PID:1221687 PID:1205776 percent identity: 34.91; identified by sequence similarity; putative; Belongs to the peptidase S49 family.
 
   
 0.534
thiL
Thiamine monphosphate kinase (thiL); Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1; Belongs to the thiamine-monophosphate kinase family.
 
     0.526
MJ_0990
Conserved hypothetical protein; Similar to GB:L13279 SP:P31065 PID:290415 GB:U00096 PID:1788239 percent identity: 39.13; identified by sequence similarity; putative; Belongs to the sulfur carrier protein TusA family.
     
 0.512
MJ_1330
Conserved hypothetical protein; Similar to GB:AE000666 percent identity: 54.47; identified by sequence similarity; putative.
     
 0.485
MJ_1332
GTP-binding protein, member of GTP1/OBG-family; Similar to SP:P42942 PID:1165215 PID:1323377 PID:790501 percent identity: 39.69; identified by sequence similarity; putative; Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family.
  
  
 0.475
metG
methionyl-tRNA synthetase (metS); Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation.
     
 0.473
uppS
Conserved hypothetical protein; Catalyzes the sequential condensation of isopentenyl diphosphate (IPP) with geranylgeranyl diphosphate (GGPP) to yield (2Z,6Z,10Z,14Z,18Z,22Z,26Z,30E,34E,38E)-undecaprenyl diphosphate (tritrans,heptacis-UPP). It is probably the precursor of glycosyl carrier lipids.
     
 0.463
MJ_0867
Conserved hypothetical protein; Catalyzes the methylthiolation of N6- threonylcarbamoyladenosine (t(6)A), leading to the formation of 2- methylthio-N6-threonylcarbamoyladenosine (ms(2)t(6)A) at position 37 in tRNAs that read codons beginning with adenine.
     
 0.461
Your Current Organism:
Methanocaldococcus jannaschii
NCBI taxonomy Id: 243232
Other names: M. jannaschii DSM 2661, Methanocaldococcus jannaschii DSM 2661, Methanocaldococcus jannaschii str. DSM 2661, Methanococcus jannaschii DSM 2661
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