Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
MJ_1178Conserved hypothetical protein; Similar to SP:P42982 PID:755606 PID:1146237 GB:AL009126 percent identity: 26.36; identified by sequence similarity; putative; Belongs to the glycosyltransferase group 1 family. Glycosyltransferase 4 subfamily. (351 aa)    
Predicted Functional Partners:
thiDN
Conserved hypothetical protein; Catalyzes the phosphorylation of hydroxymethylpyrimidine phosphate (HMP-P) to HMP-PP, and of HMP to HMP-P. In the C-terminal section; belongs to the ThiN family.
  
  
 0.845
ribL
Glycerol-3-phosphate cytidyltransferase (taqD); Catalyzes the transfer of the AMP portion of ATP to flavin mononucleotide (FMN) to produce flavin adenine dinucleotide (FAD) coenzyme. To a lesser extent, is also able to utilize other nucleotides such as CTP and GTP as substrates, producing the modified coenzymes, flavin cytosine dinucleotide (FCD) and flavin guanine dinucleotide (FGD), respectively. Does not catalyze the reverse reaction to produce FMN and ATP from FAD and PPi. Does not function as a glycerol-3- phosphate cytidylyltransferase, as previously annotated in the complete gen [...]
  
  
 0.809
MJ_1631
Glycogen phosphorylase (glgP); Similar to GB:Z25795 SP:P39123 PID:397492 PID:2293140 GB:AL009126 percent identity: 27.95; identified by sequence similarity; putative; Belongs to the glycogen phosphorylase family.
  
 
 0.686
MJ_1177
Conserved hypothetical protein; Similar to GB:M94110 SP:Q04454 PID:142791 percent identity: 24.44; identified by sequence similarity; putative.
 
   
 0.645
MJ_1068
Polysaccharide biosynthesis protein (capF) isolog; Similar to GB:U10927 SP:P39855 PID:506702 percent identity: 21.66; identified by sequence similarity; putative.
 
  
 0.608
MJ_1554
Conserved hypothetical protein; Similar to GB:AE000782 percent identity: 42.23; identified by sequence similarity; putative.
  
 0.597
MJ_1054
UDP-glucose dehydrogenase, putative; Similar to GP:1651923 percent identity: 43.32; identified by sequence similarity; putative.
 
  
 0.572
topA
DNA topoisomerase I (topA) {Bacillus subtilis; Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA- (5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken stra [...]
 
 
 
 0.568
MJ_1059
Capsular polysaccharide biosynthsis protein M; Similar to GB:U10927 SP:P39862 PID:506709 percent identity: 31.91; identified by sequence similarity; putative; Belongs to the glycosyltransferase group 1 family. Glycosyltransferase 4 subfamily.
  
     0.562
MJ_1375
SpoVB isolog; Similar to GB:D26185 SP:P37555 PID:467446 GB:AL009126 percent identity: 23.61; identified by sequence similarity; putative.
 
  
 0.556
Your Current Organism:
Methanocaldococcus jannaschii
NCBI taxonomy Id: 243232
Other names: M. jannaschii DSM 2661, Methanocaldococcus jannaschii DSM 2661, Methanocaldococcus jannaschii str. DSM 2661, Methanococcus jannaschii DSM 2661
Server load: low (10%) [HD]