STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ribLGlycerol-3-phosphate cytidyltransferase (taqD); Catalyzes the transfer of the AMP portion of ATP to flavin mononucleotide (FMN) to produce flavin adenine dinucleotide (FAD) coenzyme. To a lesser extent, is also able to utilize other nucleotides such as CTP and GTP as substrates, producing the modified coenzymes, flavin cytosine dinucleotide (FCD) and flavin guanine dinucleotide (FGD), respectively. Does not catalyze the reverse reaction to produce FMN and ATP from FAD and PPi. Does not function as a glycerol-3- phosphate cytidylyltransferase, as previously annotated in the complete gen [...] (149 aa)    
Predicted Functional Partners:
ribK
Conserved hypothetical protein; Catalyzes the CTP-dependent phosphorylation of riboflavin (vitamin B2) to form flavin mononucleotide (FMN). Can also utilize UTP as the phosphate donor, although less efficiently, and it is unclear if ATP and GTP can also serve as substrates or not.
  
  
 0.990
MJ_1177
Conserved hypothetical protein; Similar to GB:M94110 SP:Q04454 PID:142791 percent identity: 24.44; identified by sequence similarity; putative.
       0.875
MJ_0175
Conserved hypothetical protein; Similar to GB:AE000782 percent identity: 33.71; identified by sequence similarity; putative.
      
 0.804
MJ_1178
Conserved hypothetical protein; Similar to SP:P42982 PID:755606 PID:1146237 GB:AL009126 percent identity: 26.36; identified by sequence similarity; putative; Belongs to the glycosyltransferase group 1 family. Glycosyltransferase 4 subfamily.
  
  
 0.776
ribH
Riboflavin synthase beta chain (ribH); Catalyzes the formation of 6,7-dimethyl-8-ribityllumazine by condensation of 5-amino-6-(D-ribitylamino)uracil with 3,4-dihydroxy-2- butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin; Belongs to the DMRL synthase family.
  
  
 0.743
pyrD
Dihydroorotase dehydrogenase (pyrD); Catalyzes the conversion of dihydroorotate to orotate with NAD(+) as electron acceptor; Belongs to the dihydroorotate dehydrogenase family. Type 1 subfamily.
     
 0.672
MJ_0959
Aspartate aminotransferase (aspC); Similar to PID:704449 GB:AE000666 percent identity: 54.69; identified by sequence similarity; putative.
  
  
 0.672
MJ_1137
Conserved hypothetical protein; Similar to GB:U02878 SP:P41078 PID:434679 percent identity: 30.52; identified by sequence similarity; putative.
   
 
 0.603
MJ_1336
Hypothetical protein; Identified by GeneMark; putative; M. jannaschii predicted coding region MJ1336.
 
   
 0.502
MJ_0283
Nucleotide-binding protein; Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP; Belongs to the Mrp/NBP35 ATP-binding proteins family.
     
 0.451
Your Current Organism:
Methanocaldococcus jannaschii
NCBI taxonomy Id: 243232
Other names: M. jannaschii DSM 2661, Methanocaldococcus jannaschii DSM 2661, Methanocaldococcus jannaschii str. DSM 2661, Methanococcus jannaschii DSM 2661
Server load: low (32%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.