STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
MJ_1185Putative aldehyde ferredoxin oxidoreductase (aor); Similar to PID:736274 percent identity: 26.51; identified by sequence similarity; putative; Belongs to the AOR/FOR family. (622 aa)    
Predicted Functional Partners:
fbp
Conserved hypothetical protein; Catalyzes two subsequent steps in gluconeogenesis: the aldol condensation of dihydroxyacetone phosphate (DHAP) and glyceraldehyde-3- phosphate (GA3P) to fructose-1,6-bisphosphate (FBP), and the dephosphorylation of FBP to fructose-6-phosphate (F6P).
 
  
 0.951
gap
Glyceraldehyde 3-phosphate dehydrogenase; Similar to SP:P10618 PID:149792 percent identity: 60.00; identified by sequence similarity; putative.
    
 0.950
pgk
Phosphoglycerate kinase (pgk); Similar to GB:M55529 SP:P20971 PID:149808 percent identity: 56.76; identified by sequence similarity; putative; Belongs to the phosphoglycerate kinase family.
    
 0.930
tpiA
Triosephosphate isomerase; Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D- glyceraldehyde-3-phosphate (G3P).
    
  0.913
aroA
Conserved hypothetical protein; Catalyzes a transaldol reaction between 6-deoxy-5- ketofructose 1-phosphate (DKFP) and L-aspartate semialdehyde (ASA) with an elimination of hydroxypyruvaldehyde phosphate to yield 2-amino-3,7- dideoxy-D-threo-hept-6-ulosonate (ADH). Plays a key role in an alternative pathway of the biosynthesis of 3-dehydroquinate (DHQ), which is involved in the canonical pathway for the biosynthesis of aromatic amino acids. Can also catalyze the cleavage of fructose-1,6- bisphosphate (FBP) to glyceraldehyde-3-phosphate (GAP) and dihydroxyacetone phosphate (DHAP).
    
 0.910
MJ_1585
Conserved hypothetical protein; Catalyzes the transaldolisation of either fructose-1-P or fructose-1,6-bisphosphate with methylglyoxal to produce 6-deoxy-5- ketofructose-1-phosphate (DKFP). Also catalyzes the reversible aldol condensation of dihydroxyacetone phosphate (DHAP or glycerone- phosphate) with glyceraldehyde 3-phosphate (G3P or GAP) to produce fructose 1,6-bisphosphate (FBP).
    
 0.910
apgM2
BcpC phosphonopyruvate decarboxylase; Catalyzes the interconversion of 2-phosphoglycerate and 3- phosphoglycerate.
    
  0.902
apgM1
Phosphonopyruvate decarboxylase (bcpC); Catalyzes the interconversion of 2-phosphoglycerate and 3- phosphoglycerate.
    
  0.902
MJ_0264
Carbon monoxide dehydrogenase, iron sulfur subunit CooF-1 (cooF1); Similar to GB:M90421 SP:P31894 PID:1171263 PID:1498747 percent identity: 36.04; identified by sequence similarity; putative.
   
 
 0.818
pgi
Glucose-6-phosphate isomerase; Catalyzes the isomerization of glucose-6-P to fructose-6-P.
    
  0.805
Your Current Organism:
Methanocaldococcus jannaschii
NCBI taxonomy Id: 243232
Other names: M. jannaschii DSM 2661, Methanocaldococcus jannaschii DSM 2661, Methanocaldococcus jannaschii str. DSM 2661, Methanococcus jannaschii DSM 2661
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