STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
MJ_1196asoB protein; Similar to PID:984560 percent identity: 23.53; identified by sequence similarity; putative. (366 aa)    
Predicted Functional Partners:
truB
Centromere/microtubule-binding protein (cbf5); Could be responsible for synthesis of pseudouridine from uracil-55 in the psi GC loop of transfer RNAs.
   
 
 0.732
thrS
threonyl-tRNA synthetase (thrS); Catalyzes the attachment of threonine to tRNA(Thr) in a two- step reaction: L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr). Also activates L-serine, but does not detectably transfer it to tRNA(Thr). Edits incorrectly charged L-seryl-tRNA(Thr) via its editing domain. Has no activity on correctly acylated L-seryl-tRNA(Ser) or L-threonyl- tRNA(Thr). Deacylates correctly charged glycyl- tRNA(Gly), but not glycyl-tRNA(Gly)(2'-dA76) (the terminal 2'-OH of tRNA adenine 76 has been dehydroxylated) nor [...]
     
 0.597
leuA
2-isopropylmalate synthase (leuA); Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3- hydroxy-4-methylpentanoate (2-isopropylmalate).
   
 
 0.590
mfnA
Group II decarboxylase; Catalyzes the decarboxylation of L-tyrosine to produce tyramine for methanofuran biosynthesis. Can also catalyze the decarboxylation of L-aspartate to produce beta-alanine for coenzyme A (CoA) biosynthesis.
 
  
 0.487
trpF
Phosphoribosylanthranilate isomerase (trpF); Similar to GB:M83788 PID:149038 SP:P52563 percent identity: 41.23; identified by sequence similarity; putative; Belongs to the TrpF family.
   
 
 0.486
MJ_0920
GTP-binding protein homologue (yphC); Similar to PID:1146219 SP:P50743 GB:AL009126 percent identity: 26.99; identified by sequence similarity; putative.
  
 
 0.447
MJ_1226
Plasma membrane ATPase 1 (aha1); Similar to SP:P20649 percent identity: 44.42; identified by sequence similarity; putative; Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IIIA subfamily.
   
 
 0.416
MJ_1137
Conserved hypothetical protein; Similar to GB:U02878 SP:P41078 PID:434679 percent identity: 30.52; identified by sequence similarity; putative.
 
 
   0.408
Your Current Organism:
Methanocaldococcus jannaschii
NCBI taxonomy Id: 243232
Other names: M. jannaschii DSM 2661, Methanocaldococcus jannaschii DSM 2661, Methanocaldococcus jannaschii str. DSM 2661, Methanococcus jannaschii DSM 2661
Server load: low (36%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.