STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
MJ_1198Conserved hypothetical protein; Similar to GB:L77117 PID:1591827 percent identity: 100.00; identified by sequence similarity; putative. (761 aa)    
Predicted Functional Partners:
ribL
Glycerol-3-phosphate cytidyltransferase (taqD); Catalyzes the transfer of the AMP portion of ATP to flavin mononucleotide (FMN) to produce flavin adenine dinucleotide (FAD) coenzyme. To a lesser extent, is also able to utilize other nucleotides such as CTP and GTP as substrates, producing the modified coenzymes, flavin cytosine dinucleotide (FCD) and flavin guanine dinucleotide (FGD), respectively. Does not catalyze the reverse reaction to produce FMN and ATP from FAD and PPi. Does not function as a glycerol-3- phosphate cytidylyltransferase, as previously annotated in the complete gen [...]
       0.685
MJ_1401
Putative ATP dependent RNA helicase; Similar to SP:P32639 PID:603413 percent identity: 29.62; identified by sequence similarity; putative; Belongs to the DEAD box helicase family.
  
    0.675
MJ_0841
Conserved hypothetical protein; Radical SAM methyltransferase that is responsible for the C(5)-methylation of 'Arg-274' of the methyl-coenzyme M reductase (MCR) subunit alpha McrA. This post-translational methylation, despite being not essential in vivo, plays a role for the stability and structural integrity of MCR.
  
     0.662
MJ_0981
Conserved hypothetical protein; Similar to GB:AE000666 percent identity: 28.18; identified by sequence similarity; putative.
  
     0.624
MJ_0558
Conserved hypothetical protein; Similar to GB:AE000666 percent identity: 41.96; identified by sequence similarity; putative.
  
     0.582
rnp3
Hypothetical protein; Part of ribonuclease P, a protein complex that generates mature tRNA molecules by cleaving their 5'-ends. Belongs to the eukaryotic/archaeal RNase P protein component 3 family.
  
     0.525
MJ_0421
Conserved hypothetical protein; Similar to GP:1786625 percent identity: 35.10; identified by sequence similarity; putative.
  
     0.516
mtrH
N5-methyl-tetrahydromethanopterin:coenzyme M methyltransferase, subunit H (mtrH); Part of a complex that catalyzes the formation of methyl- coenzyme M and tetrahydromethanopterin from coenzyme M and methyl- tetrahydromethanopterin. This is an energy-conserving, sodium-ion translocating step. MtrH catalyzes the transfer of the methyl group from methyl-tetrahydromethanopterin to the corrinoid prosthetic group of MtrA.
  
     0.515
rpl40e
LSU ribosomal protein L40E (CEP52); Similar to PIR:B48470 percent identity: 61.11; identified by sequence similarity; putative; Belongs to the eukaryotic ribosomal protein eL40 family.
  
     0.489
MJ_1646
Pyrimidine biosynthesis protein, putative; Similar to GP:340170 percent identity: 31.30; identified by sequence similarity; putative; Belongs to the purine/pyrimidine phosphoribosyltransferase family.
  
     0.467
Your Current Organism:
Methanocaldococcus jannaschii
NCBI taxonomy Id: 243232
Other names: M. jannaschii DSM 2661, Methanocaldococcus jannaschii DSM 2661, Methanocaldococcus jannaschii str. DSM 2661, Methanococcus jannaschii DSM 2661
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.