STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
MJ_1198Conserved hypothetical protein; Similar to GB:L77117 PID:1591827 percent identity: 100.00; identified by sequence similarity; putative. (761 aa)    
Predicted Functional Partners:
recJ
Conserved hypothetical protein; Single-stranded-DNA-specific exonuclease.
  
  
 0.827
hjc
Hypothetical protein; A structure-specific endonuclease that resolves Holliday junction (HJ) intermediates during genetic recombination. Cleaves 4-way DNA junctions introducing paired nicks in opposing strands, leaving a 5'-terminal phosphate and a 3'-terminal hydroxyl group that are ligated to produce recombinant products; Belongs to the Holliday junction resolvase Hjc family.
      
 0.677
MJ_1401
Putative ATP dependent RNA helicase; Similar to SP:P32639 PID:603413 percent identity: 29.62; identified by sequence similarity; putative; Belongs to the DEAD box helicase family.
  
    0.677
MJ_0841
Conserved hypothetical protein; Radical SAM methyltransferase that is responsible for the C(5)-methylation of 'Arg-274' of the methyl-coenzyme M reductase (MCR) subunit alpha McrA. This post-translational methylation, despite being not essential in vivo, plays a role for the stability and structural integrity of MCR.
  
     0.662
MJ_0981
Conserved hypothetical protein; Similar to GB:AE000666 percent identity: 28.18; identified by sequence similarity; putative.
  
     0.624
MJ_0558
Conserved hypothetical protein; Similar to GB:AE000666 percent identity: 41.96; identified by sequence similarity; putative.
  
     0.582
rnp3
Hypothetical protein; Part of ribonuclease P, a protein complex that generates mature tRNA molecules by cleaving their 5'-ends. Belongs to the eukaryotic/archaeal RNase P protein component 3 family.
  
     0.525
MJ_0421
Conserved hypothetical protein; Similar to GP:1786625 percent identity: 35.10; identified by sequence similarity; putative.
  
     0.516
mtrH
N5-methyl-tetrahydromethanopterin:coenzyme M methyltransferase, subunit H (mtrH); Part of a complex that catalyzes the formation of methyl- coenzyme M and tetrahydromethanopterin from coenzyme M and methyl- tetrahydromethanopterin. This is an energy-conserving, sodium-ion translocating step. MtrH catalyzes the transfer of the methyl group from methyl-tetrahydromethanopterin to the corrinoid prosthetic group of MtrA.
  
     0.515
rpl40e
LSU ribosomal protein L40E (CEP52); Similar to PIR:B48470 percent identity: 61.11; identified by sequence similarity; putative; Belongs to the eukaryotic ribosomal protein eL40 family.
  
     0.489
Your Current Organism:
Methanocaldococcus jannaschii
NCBI taxonomy Id: 243232
Other names: M. jannaschii DSM 2661, Methanocaldococcus jannaschii DSM 2661, Methanocaldococcus jannaschii str. DSM 2661, Methanococcus jannaschii DSM 2661
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