STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
MJ_1200Modification methylase, type II R/M system; Similar to SP:P05302 percent identity: 40.20; identified by sequence similarity; putative. (366 aa)    
Predicted Functional Partners:
MJ_1388
Adenosylhomocysteinase (ahcY); Catalyzes the hydrolysis of S-inosyl-L-homocysteine (SIH) to L-homocysteine (Hcy) and inosine. Likely functions in a S-adenosyl-L- methionine (SAM) recycling pathway from S-adenosyl-L-homocysteine (SAH) produced from SAM-dependent methylation reactions. Can also catalyze the reverse reaction in vitro, i.e. the synthesis of SIH from Hcy and inosine. Is specific for SIH and inosine as it is unable to either hydrolyze SAH or synthesize SAH from adenosine and Hcy. Belongs to the adenosylhomocysteinase family.
    
 0.913
MJ_0563
Modification methylase, type II R/M system; Similar to SP:P50192 percent identity: 35.29; identified by sequence similarity; putative.
  
  
 
0.904
speH
Conserved hypothetical protein; Catalyzes the decarboxylation of S-adenosylmethionine to S- adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine; Belongs to the prokaryotic AdoMetDC family. Type 1 subfamily.
     
  0.900
mjaIIIM
Modification methylase, type II R/M system 2; This methylase recognizes the double-stranded sequence GATC, causes specific methylation on A-2 on both strands, and protects the DNA from cleavage by the MjaIII endonuclease; Belongs to the N(4)/N(6)-methyltransferase family.
     
 0.900
mat
Conserved hypothetical protein; Catalyzes the formation of S-adenosylmethionine from methionine and ATP.
     
  0.900
mjaVIM
Modification methylase, type II R/M system; This methylase recognizes the double-stranded sequence CCGG, causes specific methylation on C-? on both strands, and protects the DNA from cleavage by the MjaVI endonuclease; Belongs to the N(4)/N(6)-methyltransferase family. N(4) subfamily.
  
  
 0.900
MJ_1199
Hypothetical protein; Invalid gene; identified by GeneMark; putative; M. jannaschii predicted coding region MJ1199; To A.pernix APE2001.
       0.685
rpl24e
LSU ribosomal protein L24E; Binds to the 23S rRNA.
       0.584
dnaG
Conserved hypothetical protein; RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication.
  
  
 0.523
rps28e
SSU ribosomal protein S28E; Similar to GB:L05091 GB:U58682 SP:P25112 PID:1518637 PID:337403 percent identity: 53.45; identified by sequence similarity; putative; Belongs to the eukaryotic ribosomal protein eS28 family.
     
 0.509
Your Current Organism:
Methanocaldococcus jannaschii
NCBI taxonomy Id: 243232
Other names: M. jannaschii DSM 2661, Methanocaldococcus jannaschii DSM 2661, Methanocaldococcus jannaschii str. DSM 2661, Methanococcus jannaschii DSM 2661
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