Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
MJ_1210Conserved hypothetical protein; Similar to GB:AE000782 percent identity: 46.03; identified by sequence similarity; putative. (258 aa)    
Predicted Functional Partners:
rpl44e
LSU ribosomal protein L44E; Binds to the 23S rRNA.
 
     0.816
priS
DNA primase, putative; Catalytic subunit of DNA primase, an RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication. The small subunit contains the primase catalytic core and has DNA synthesis activity on its own. Binding to the large subunit stabilizes and modulates the activity, increasing the rate of DNA synthesis while decreasing the length of the DNA fragments, and conferring RNA synthesis capability. The DNA polymerase activity may enable DNA primase to also catalyze primer extension after primer synthesis. May [...]
 
     0.786
eif2a
Translation initiation factor aIF-2, subunit alpha (aif2A); eIF-2 functions in the early steps of protein synthesis by forming a ternary complex with GTP and initiator tRNA; Belongs to the eIF-2-alpha family.
 
    0.781
MJ_1211
Hypothetical protein; Identified by GeneMark; putative; M. jannaschii predicted coding region MJ1211.
       0.740
pcn
Proliferating-cell nuclear antigen (pol30); Sliding clamp subunit that acts as a moving platform for DNA processing. Responsible for tethering the catalytic subunit of DNA polymerase and other proteins to DNA during high-speed replication. Belongs to the PCNA family.
 
     0.722
MJ_0043
Intein containing hypothetical protein; Similar to GP:1303985 percent identity: 41.38; identified by sequence similarity; putative.
       0.685
nop10
Conserved hypothetical protein; Involved in ribosome biogenesis; more specifically in 18S rRNA pseudouridylation and in cleavage of pre-rRNA; Belongs to the NOP10 family.
       0.685
rps27e
SSU ribosomal protein S27E; Similar to SP:P35997 SP:P38711 PID:2131116 PID:486271 PID:500694 percent identity: 42.59; identified by sequence similarity; putative.
       0.685
MJ_1569
Cobalamin biosynthesis protein (cbiM); May be involved in metal transport; Belongs to the CbiM family.
       0.678
MJ_1571
Cobalt transport protein (cbiQ); Similar to GP:1419077 percent identity: 27.87; identified by sequence similarity; putative.
       0.644
Your Current Organism:
Methanocaldococcus jannaschii
NCBI taxonomy Id: 243232
Other names: M. jannaschii DSM 2661, Methanocaldococcus jannaschii DSM 2661, Methanocaldococcus jannaschii str. DSM 2661, Methanococcus jannaschii DSM 2661
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