Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
pssACDP-diacylglycerol--serine O-phosphatidyltransferase (pssA); Similar to GB:D38022 SP:P39823 PID:1065993 GB:AL009126 percent identity: 43.51; identified by sequence similarity; putative; Belongs to the CDP-alcohol phosphatidyltransferase class-I family. (201 aa)    
Predicted Functional Partners:
asd-2
Phosphatidylserine decarboxylase proenzyme 2 precursor (psd2); Catalyzes the formation of archaetidylethanolamine (PtdEtn) from archaetidylserine (PtdSer); Belongs to the phosphatidylserine decarboxylase family. PSD-A subfamily.
 
  
 0.948
carS
Conserved hypothetical protein; Catalyzes the formation of CDP-2,3-bis-(O-geranylgeranyl)-sn- glycerol (CDP-archaeol) from 2,3-bis-(O-geranylgeranyl)-sn-glycerol 1- phosphate (DGGGP) and CTP. This reaction is the third ether-bond- formation step in the biosynthesis of archaeal membrane lipids.
 
  
  0.936
MJ_1213
Hypothetical protein; Identified by GeneMark; putative; M. jannaschii predicted coding region MJ1213; To M.jannaschii MJ0123 and A.aeolicus AA15.
       0.768
MJ_1214
Type I restriction-modification enzyme 1, R subunit; Similar to GB:L42023 PID:1007240 PID:1221415 PID:1205524 PID:1574743 percent identity: 27.55; identified by sequence similarity; putative.
       0.767
mptD
Conserved hypothetical protein; Catalyzes the conversion of 7,8-dihydroneopterin (H2Neo) to 6-hydroxymethyl-7,8-dihydropterin (6-HMD).
       0.685
tfs
Transcription-associated protein ('TFIIS'); Induces RNA cleavage activity in the RNA polymerase. In its presence, the cleavage activity of the RNA polymerase truncates the RNA back to position +15 in a stepwise manner by releasing mainly dinucleotides from the 3'-end of the nascent RNA. The truncated RNAs are able to continue elongation. Involved in transcriptional proofreading and fidelity. Misincorporation of nucleotides during elongation of transcription leads to arrested elongation complexes which are rescued by TFS-promoted removal of a dinucleotide from the 3'-end. TFS is able to [...]
       0.684
nudF
Mutator MutT protein, putative (mutT); Similar to GB:D10483 SP:P08337 GB:M20791 GB:X04831 PID:147795 percent identity: 40.28; identified by sequence similarity; putative.
       0.674
MJ_1211
Hypothetical protein; Identified by GeneMark; putative; M. jannaschii predicted coding region MJ1211.
       0.646
MJ_1215
Conserved hypothetical protein; Similar to PID:1653122 percent identity: 33.33; identified by sequence similarity; putative; Belongs to the M.jannaschii MJ0126/MJ0128/MJ0141/MJ0435/MJ0604/MJ1215/MJ1217/MJ1305/MJ1379 family.
       0.626
MJ_1217
Conserved hypothetical protein; Similar to PID:1653122 percent identity: 33.70; identified by sequence similarity; putative; Belongs to the M.jannaschii MJ0126/MJ0128/MJ0141/MJ0435/MJ0604/MJ1215/MJ1217/MJ1305/MJ1379 family.
       0.621
Your Current Organism:
Methanocaldococcus jannaschii
NCBI taxonomy Id: 243232
Other names: M. jannaschii DSM 2661, Methanocaldococcus jannaschii DSM 2661, Methanocaldococcus jannaschii str. DSM 2661, Methanococcus jannaschii DSM 2661
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