STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
pssACDP-diacylglycerol--serine O-phosphatidyltransferase (pssA); Similar to GB:D38022 SP:P39823 PID:1065993 GB:AL009126 percent identity: 43.51; identified by sequence similarity; putative; Belongs to the CDP-alcohol phosphatidyltransferase class-I family. (201 aa)    
Predicted Functional Partners:
asd-2
Phosphatidylserine decarboxylase proenzyme 2 precursor (psd2); Catalyzes the formation of archaetidylethanolamine (PtdEtn) from archaetidylserine (PtdSer); Belongs to the phosphatidylserine decarboxylase family. PSD-A subfamily.
 
 
 0.992
MJ_1594
Phosphoserine phosphatase (serB); Similar to SP:P06862 GB:X03046 PID:42948 PID:537228 GB:U00096 percent identity: 39.80; identified by sequence similarity; putative.
    
 0.917
glyA
Serine hydroxymethyltransferase (glyA); Catalyzes the reversible interconversion of serine and glycine with tetrahydromethanopterin (H4MPT) serving as the one-carbon carrier. The use of tetrahydrofolate (THF or H4PteGlu) as the pteridine substrate is 450-fold less efficient than that of H4MPT. Also exhibits a pteridine-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. Thus, is able to catalyze the cleavage of L-allo-threonine and L-threo- beta-phenylserine; Belongs to the SHMT family.
    
 0.908
trpB
Tryptophan synthase beta subunit (trpB); The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine.
    
 0.904
trpA
Tryptophan synthase alpha subunit (trpA); The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3-phosphate. Belongs to the TrpA family.
    
  0.902
MJ_1213
Hypothetical protein; Identified by GeneMark; putative; M. jannaschii predicted coding region MJ1213; To M.jannaschii MJ0123 and A.aeolicus AA15.
       0.768
MJ_1214
Type I restriction-modification enzyme 1, R subunit; Similar to GB:L42023 PID:1007240 PID:1221415 PID:1205524 PID:1574743 percent identity: 27.55; identified by sequence similarity; putative.
       0.767
MJ_1211
Hypothetical protein; Identified by GeneMark; putative; M. jannaschii predicted coding region MJ1211.
       0.734
MJ_1215
Conserved hypothetical protein; Similar to PID:1653122 percent identity: 33.33; identified by sequence similarity; putative; Belongs to the M.jannaschii MJ0126/MJ0128/MJ0141/MJ0435/MJ0604/MJ1215/MJ1217/MJ1305/MJ1379 family.
       0.626
MJ_1217
Conserved hypothetical protein; Similar to PID:1653122 percent identity: 33.70; identified by sequence similarity; putative; Belongs to the M.jannaschii MJ0126/MJ0128/MJ0141/MJ0435/MJ0604/MJ1215/MJ1217/MJ1305/MJ1379 family.
       0.621
Your Current Organism:
Methanocaldococcus jannaschii
NCBI taxonomy Id: 243232
Other names: M. jannaschii DSM 2661, Methanocaldococcus jannaschii DSM 2661, Methanocaldococcus jannaschii str. DSM 2661, Methanococcus jannaschii DSM 2661
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