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STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
MJ_1222dolichol-P-glucose synthetase isolog; Similar to SP:P40350 PID:1181261 PID:1370470 PID:535141 percent identity: 31.75; identified by sequence similarity; putative. (243 aa)    
Predicted Functional Partners:
MJ_1223
Hypothetical protein; Identified by GeneMark; putative; M. jannaschii predicted coding region MJ1223.
       0.955
MJ_1224
Conserved hypothetical protein; Similar to GB:AE000666 percent identity: 44.72; identified by sequence similarity; putative; Belongs to the UPF0216 family.
       0.797
MJ_0757
Conserved hypothetical protein; Is able to catalyze the biosynthesis of dTMP using dUMP, tetrahydrofolate and formaldehyde in vitro, i.e. a reaction equivalent to that catalyzed by bacterial thymidylate synthases (EC 2.1.1.45). However, M.jannaschii like most methanogenic Archaea lacks folates, thus the physiological cosubstrate is unknown but is likely one of the non-methylated methanopterin biosynthetic intermediates.
     
 0.622
MJ_0496
Hypothetical protein; Identified by GeneMark; putative; M. jannaschii predicted coding region MJ0496.
      
 0.615
MJ_1580
Conserved hypothetical protein; Similar to GB:AE000666 percent identity: 29.52; identified by sequence similarity; putative.
 
   
 0.592
rtcB
Conserved hypothetical protein; GTP-dependent RNA ligase that is involved in tRNA splicing and RNA repair. Joins RNA with 2',3'-cyclic-phosphate or 3'-phosphate ends to RNA with 5'-hydroxy ends; Belongs to the RtcB family.
  
    0.591
MJ_0211
UDP-glucose 4-epimerase (galE); Involved in the metabolism of galactose. Catalyzes the conversion of UDP-galactose (UDP-Gal) to UDP-glucose (UDP-Glc) through a mechanism involving the transient reduction of NAD (By similarity). Belongs to the NAD(P)-dependent epimerase/dehydratase family.
 
 
 0.517
MJ_1178
Conserved hypothetical protein; Similar to SP:P42982 PID:755606 PID:1146237 GB:AL009126 percent identity: 26.36; identified by sequence similarity; putative; Belongs to the glycosyltransferase group 1 family. Glycosyltransferase 4 subfamily.
 
 
 0.506
MJ_1069
Galactosyltransferase isolog; Similar to GP:1486283 percent identity: 26.38; identified by sequence similarity; putative; Belongs to the glycosyltransferase group 1 family. Glycosyltransferase 4 subfamily.
 
 
 0.480
MJ_1068
Polysaccharide biosynthesis protein (capF) isolog; Similar to GB:U10927 SP:P39855 PID:506702 percent identity: 21.66; identified by sequence similarity; putative.
 
  
 0.479
Your Current Organism:
Methanocaldococcus jannaschii
NCBI taxonomy Id: 243232
Other names: M. jannaschii DSM 2661, Methanocaldococcus jannaschii DSM 2661, Methanocaldococcus jannaschii str. DSM 2661, Methanococcus jannaschii DSM 2661
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