Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
MJ_1224Conserved hypothetical protein; Similar to GB:AE000666 percent identity: 44.72; identified by sequence similarity; putative; Belongs to the UPF0216 family. (139 aa)    
Predicted Functional Partners:
MJ_1222
dolichol-P-glucose synthetase isolog; Similar to SP:P40350 PID:1181261 PID:1370470 PID:535141 percent identity: 31.75; identified by sequence similarity; putative.
       0.780
MJ_1223
Hypothetical protein; Identified by GeneMark; putative; M. jannaschii predicted coding region MJ1223.
       0.780
atpD
H+-transporting ATP synthase, subunit D (atpD); Produces ATP from ADP in the presence of a proton gradient across the membrane.
       0.575
MJ_0694
Conserved hypothetical protein; Similar to SP:Q12499 PID:1420682 PID:940841 percent identity: 43.15; identified by sequence similarity; putative.
       0.575
flpA
Fibrillarin (fib); Involved in pre-rRNA and tRNA processing. Utilizes the methyl donor S-adenosyl-L-methionine to catalyze the site-specific 2'-hydroxyl methylation of ribose moieties in rRNA and tRNA. Site specificity is provided by a guide RNA that base pairs with the substrate. Methylation occurs at a characteristic distance from the sequence involved in base pairing with the guide RNA.
       0.575
trm1
N2,N2-dimethylguanosine tRNA methyltransferase (trm1); Dimethylates a single guanine residue at position 26 of a number of tRNAs using S-adenosyl-L-methionine as donor of the methyl groups; Belongs to the class I-like SAM-binding methyltransferase superfamily. Trm1 family.
       0.575
MJ_1164
Conserved hypothetical protein; Similar to GB:AE000666 percent identity: 36.75; identified by sequence similarity; putative.
       0.575
glnA
Glutamine synthetase (glnA); Probably involved in nitrogen metabolism via ammonium assimilation. Catalyzes the ATP-dependent biosynthesis of glutamine from glutamate and ammonia. Beta-glutamate is a much poorer substrate than alpha-glutamate.
       0.575
MJ_1225
Conserved hypothetical protein; Similar to SP:P15889 PID:48226 percent identity: 23.19; identified by sequence similarity; putative.
       0.562
MJ_1226
Plasma membrane ATPase 1 (aha1); Similar to SP:P20649 percent identity: 44.42; identified by sequence similarity; putative; Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IIIA subfamily.
       0.512
Your Current Organism:
Methanocaldococcus jannaschii
NCBI taxonomy Id: 243232
Other names: M. jannaschii DSM 2661, Methanocaldococcus jannaschii DSM 2661, Methanocaldococcus jannaschii str. DSM 2661, Methanococcus jannaschii DSM 2661
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