Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
MJ_1225Conserved hypothetical protein; Similar to SP:P15889 PID:48226 percent identity: 23.19; identified by sequence similarity; putative. (280 aa)    
Predicted Functional Partners:
MJ_1404
Hypothetical protein; Identified by GeneMark; putative; M. jannaschii predicted coding region MJ1404.
 
   
0.918
MJ_0653
Inosine-5'-monophosphate dehydrogenase (guaB); Similar to PID:1002715 SP:P50100 percent identity: 41.42; identified by sequence similarity; putative.
 
   
0.906
MJ_0450
Inosine monophosphate dehydrogenase isolog; Similar to PID:1002715 SP:P50100 percent identity: 27.56; identified by sequence similarity; putative.
  
    0.888
rpl22
LSU ribosomal protein L22P (rplV); This protein binds specifically to 23S rRNA. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome.
 
 
 0.769
rpl30e
LSU ribosomal protein L30E; Similar to SP:P14025 GB:X15970 PID:44782 percent identity: 64.71; identified by sequence similarity; putative; Belongs to the eukaryotic ribosomal protein eL30 family.
 
   0.765
rpl4
LSU ribosomal protein L4P (rplD); One of the primary rRNA binding proteins, this protein initially binds near the 5'-end of the 23S rRNA. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome.
  
 
 0.764
rps2
SSU ribosomal protein S2P; Similar to GP:1707827 percent identity: 54.69; identified by sequence similarity; putative; Belongs to the universal ribosomal protein uS2 family.
  
 
 0.763
rpl3
LSU ribosomal protein L3P (rplC); One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit; Belongs to the universal ribosomal protein uL3 family.
  
 
 0.762
rps13
SSU ribosomal protein S13P (rpsM); Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits; these bridges are implicated in subunit movement; Belongs to the universal ribosomal protein uS13 family.
  
 
 0.759
MJ_1226
Plasma membrane ATPase 1 (aha1); Similar to SP:P20649 percent identity: 44.42; identified by sequence similarity; putative; Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IIIA subfamily.
   
 
 0.758
Your Current Organism:
Methanocaldococcus jannaschii
NCBI taxonomy Id: 243232
Other names: M. jannaschii DSM 2661, Methanocaldococcus jannaschii DSM 2661, Methanocaldococcus jannaschii str. DSM 2661, Methanococcus jannaschii DSM 2661
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